BUTOFILOLOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H26FNO3
Molecular Weight	311.3916
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BUTOFILOLOL

Structure Search

SMILES

CCCC(=O)C1=C(OCC(O)CNC(C)(C)C)C=CC(F)=C1

InChI

InChIKey=NMBNQRJDEPOXCP-UHFFFAOYSA-N

InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6149195 | https://www.ncbi.nlm.nih.gov/pubmed/6130740 | https://www.ncbi.nlm.nih.gov/pubmed/6137087

Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of high blood pressure (essential hypertension). Butofilolol constitute a good therapeutic approach to hypertension in plethoric subjects when the weight reduction has failed to correct it adequately

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 87 Target ID: CHEMBL2094118 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6149195	Blocker 537

PubMed

PubMed

Title	Date	PubMed
[Beta blocking effects of butofilolol in standard exercise tests in the healthy subjects].	1982 Jul-Sep	6130740

Name

Type

Language

BUTOFILOLOL

Official Name

English

butofilolol [INN]

Common Name

English

BUTOFILOLOL [MI]

Common Name

English

1-BUTANONE, 1-(2-(3-((1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPOXY)-5-FLUOROPHENYL)-

Systematic Name

English

BUTOFILOLOL [MART.]

Common Name

English

2'-(3-(TERT-BUTYLAMINO)-2-HYDROXYPROPOXY)-5'-FLUOROBUTYROPHENONE

Systematic Name

English

CM-6805

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29576

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

Code System Code Type Description

FDA UNII

4AZC6Y5A8G

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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CAS

58930-32-8

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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NCI_THESAURUS

C77940

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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ChEMBL

CHEMBL157443

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SMS_ID

100000088654

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EVMPD

SUB06029MIG

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CAS

64552-17-6

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

SUPERSEDED

ECHA (EC/EINECS)

261-502-5

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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PUBCHEM

68838

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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WIKIPEDIA

BUTOFILOLOL

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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INN

4459

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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DRUG CENTRAL

453

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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MERCK INDEX

m607

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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Merck Index

MESH

C036631

Created by admin on Fri Dec 15 16:03:34 GMT 2023 , Edited by admin on Fri Dec 15 16:03:34 GMT 2023

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ACTIVE MOIETY


					4AZC6Y5A8G