BUTOFILOLOL

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H26FNO3
Molecular Weight	311.3916
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC(=O)C1=C(OCC(O)CNC(C)(C)C)C=CC(F)=C1

InChI

InChIKey=NMBNQRJDEPOXCP-UHFFFAOYSA-N

InChI=1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C17H26FNO3
Molecular Weight	311.3916
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6149195 | https://www.ncbi.nlm.nih.gov/pubmed/6130740 | https://www.ncbi.nlm.nih.gov/pubmed/6137087

Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of high blood pressure (essential hypertension). Butofilolol constitute a good therapeutic approach to hypertension in plethoric subjects when the weight reduction has failed to correct it adequately

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor beta 87 Target ID: CHEMBL2094118 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6149195	Blocker 537

PubMed

Title	Date	PubMed

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:03:34 GMT 2023` Edited by `admin` on `Fri Dec 15 16:03:34 GMT 2023`
Record UNII	4AZC6Y5A8G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTOFILOLOL

Official Name

English

butofilolol [INN]

Common Name

English

BUTOFILOLOL [MI]

Common Name

English

1-BUTANONE, 1-(2-(3-((1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPOXY)-5-FLUOROPHENYL)-

Systematic Name

English

BUTOFILOLOL [MART.]

Common Name

English

2'-(3-(TERT-BUTYLAMINO)-2-HYDROXYPROPOXY)-5'-FLUOROBUTYROPHENONE

Systematic Name

English

CM-6805

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29576