Details
Stereochemistry | RACEMIC |
Molecular Formula | C14H20N2O2 |
Molecular Weight | 248.3208 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=C(C=CC=C1)C(=O)OCCC2CCCCN2
InChI
InChIKey=BMIJYAZXNZEMLI-UHFFFAOYSA-N
InChI=1S/C14H20N2O2/c15-13-7-2-1-6-12(13)14(17)18-10-8-11-5-3-4-9-16-11/h1-2,6-7,11,16H,3-5,8-10,15H2
Piridocaine is a piperidyl propanol ester of orthoaminobenzoic acid. The toxicity of this drug resembles that of procaine. It differs from procaine in that the minimum anesthetic dose is smaller, the minimal lethal dose larger, and duration of anesthesia longer. Subarachnoid piridocaine with and without epinephrine or ephedrine offers a simple and dependable means of obtaining any degree or extent of analgesia up to the third thoracic nerves without profound or widespread motor paralysis. The most promising clinical field of usefulness for piridocaine is obstetrics.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Anesthesia for anorectal surgery; discussion of experiences with lucaine hydrochloride. | 1952 Dec |
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Spinal analgesia with piridocaine hydrochloride for cesarean and vaginal deliveries. | 1955 Jan |
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Spinal anesthesia with piridocaine (lucaine) further investigations and refinements of technic. | 1955 May |
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Spinal analgesia with lucaine: a critical appraisal based on 6,000 cases. | 1956 Jan |
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Lucaine for obstetric anesthesia. | 1962 May-Jun |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14474052
Single dose - 30 mg
Route of Administration:
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NCI_THESAURUS |
C245
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)