Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H16ClNO3 |
| Molecular Weight | 305.756 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCC2=CC=CN=C2
InChI
InChIKey=RARQHAFNGNPQCZ-UHFFFAOYSA-N
InChI=1S/C16H16ClNO3/c1-16(2,21-14-7-5-13(17)6-8-14)15(19)20-11-12-4-3-9-18-10-12/h3-10H,11H2,1-2H3
Nicofibrate is an antilipidemic drug. Treatment of diabetics led to a significant reduction in plasma cholesterol and triglycerides and brought the lipoprotein picture back within the norm. Nicofibrate did not lead to significant increases in uricaemia nor to any worsening in carbohydrate tolerance. Nicofibrate may also lead to a significant drop in plasma prothrombinic activity.
Originator
Approval Year
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C98150
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C75259
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SUB09236MIG
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m364
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PRIMARY | Merck Index |
ACTIVE MOIETY
