U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C15H12I3NO4
Molecular Weight 650.9735
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DETROTHYRONINE

SMILES

N[C@H](CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)C(O)=O

InChI

InChIKey=AUYYCJSJGJYCDS-GFCCVEGCSA-N
InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m1/s1

HIDE SMILES / InChI
Detrothyronine is the (R)-(D)-form of triiodothyronine and has antihyperlipidaemic actions with beneficial effects upon coronary disease and hypertension. Detrothyronine has been tried in the treatment of hypercholesterolemia but its toxic effects outweigh any therapeutic advantage.

Approval Year

Sample Use Guides

Name Type Language
DETROTHYRONINE
INN   MART.  
INN  
Official Name English
D-3-(4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL)-ALANINE
Common Name English
ALANINE, 3-(4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL)-, D-
Systematic Name English
DETROTHYRONINE [MART.]
Common Name English
D-TYROSINE, O-(4-HYDROXY-3-IODOPHENYL)-3,5-DIIODO-
Systematic Name English
RATHYRONINE, (R)-
Common Name English
NSC-46046
Code English
(+)-TRIIODOTHYRONINE
Systematic Name English
detrothyronine [INN]
Common Name English
DT-3
Code English
3,3',5-TRIIODO-D-THYRONINE
Systematic Name English
DEXTROTHYRONINE
Common Name English
Code System Code Type Description
INN
1008
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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FDA UNII
46XII7C16X
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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ECHA (EC/EINECS)
227-203-9
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
PRIMARY
NCI_THESAURUS
C166730
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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PUBCHEM
71212
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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ChEMBL
CHEMBL557
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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CAS
6138-48-3
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
SUPERSEDED
CAS
5714-08-9
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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NSC
46046
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
PRIMARY
EVMPD
SUB07014MIG
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
PRIMARY
SMS_ID
100000083197
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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EPA CompTox
DTXSID501016651
Created by admin on Sat Dec 16 16:52:13 GMT 2023 , Edited by admin on Sat Dec 16 16:52:13 GMT 2023
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