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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19ClN4O
Molecular Weight 342.823
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KP-544

SMILES

NC1=NC=C(C#CC2=CC=C(Cl)C=C2)C(N[C@H]3CC[C@H](O)CC3)=N1

InChI

InChIKey=XBVOXAWRUIZEMG-WKILWMFISA-N
InChI=1S/C18H19ClN4O/c19-14-5-2-12(3-6-14)1-4-13-11-21-18(20)23-17(13)22-15-7-9-16(24)10-8-15/h2-3,5-6,11,15-16,24H,7-10H2,(H3,20,21,22,23)/t15-,16-

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: use of gangliosides, substituted pyrimidines, and mesenchymal stem cells.
2006 Jun
Wide spectrum modulation by KP-544 in models relevant for neuronal survival.
2007 Apr 16
Patents
Name Type Language
KP-544
Common Name English
2-AMINO-5-(4-CHLOROPHENYLETHYNYL)-4-(TRANS-4-HYDROXYCYCLOHEXYLAMINO)PYRIMIDINE
Systematic Name English
Code System Code Type Description
PUBCHEM
9902638
Created by admin on Sat Dec 16 18:33:23 GMT 2023 , Edited by admin on Sat Dec 16 18:33:23 GMT 2023
PRIMARY
CAS
393856-87-6
Created by admin on Sat Dec 16 18:33:23 GMT 2023 , Edited by admin on Sat Dec 16 18:33:23 GMT 2023
PRIMARY
FDA UNII
44CE82289R
Created by admin on Sat Dec 16 18:33:23 GMT 2023 , Edited by admin on Sat Dec 16 18:33:23 GMT 2023
PRIMARY