Details
Stereochemistry | ACHIRAL |
Molecular Formula | C12H6Cl4 |
Molecular Weight | 291.988 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC=C(C(Cl)=C1)C2=CC=C(Cl)C=C2Cl
InChI
InChIKey=QORAVNMWUNPXAO-UHFFFAOYSA-N
InChI=1S/C12H6Cl4/c13-7-1-3-9(11(15)5-7)10-4-2-8(14)6-12(10)16/h1-6H
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element. | 1998 Dec |
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Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. | 2001 Mar |
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Developmental exposure to polychlorinated biphenyls affects sexual behavior of rats. | 2002 Apr 15 |
|
Influence of aeration on hydrophobic organic contaminant distribution and diffusive flux in estuarine sediments. | 2003 Aug 15 |
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Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome p450 enzymes. | 2003 Dec 15 |
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Effects of PCB congeners on the immune function of Mytilus hemocytes: alterations of tyrosine kinase-mediated cell signaling. | 2003 May 8 |
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Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | 2003 Oct |
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Ortho-substituted but not coplanar PCBs rapidly kill cerebellar granule cells. | 2004 May |
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Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats. | 2004 Oct 15 |
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Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. | 2005 Jul |
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Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
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Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009 Dec 10 |
|
PCB-47, PBDE-47, and 6-OH-PBDE-47 differentially modulate human GABAA and alpha4beta2 nicotinic acetylcholine receptors. | 2010 Dec |
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Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines. | 2011 Apr |
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Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. | 2011 Oct 10 |
|
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015 Apr 1 |
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2437-79-8
Created by
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17097
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34204
Created by
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219-444-3
Created by
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4470AQR07D
Created by
admin on Fri Dec 15 17:58:34 UTC 2023 , Edited by admin on Fri Dec 15 17:58:34 UTC 2023
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DTXSID0022513
Created by
admin on Fri Dec 15 17:58:34 UTC 2023 , Edited by admin on Fri Dec 15 17:58:34 UTC 2023
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