Details
Stereochemistry | ACHIRAL |
Molecular Formula | C18H28NO5 |
Molecular Weight | 338.4186 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 1 |
SHOW SMILES / InChI
SMILES
CC[N+]2(CCOC(=O)C1=CC(OC)=C(OC)C(OC)=C1)CCCC2
InChI
InChIKey=FYDIOQNEQHPRNW-UHFFFAOYSA-N
InChI=1S/C18H28NO5/c1-5-19(8-6-7-9-19)10-11-24-18(20)14-12-15(21-2)17(23-4)16(13-14)22-3/h12-13H,5-11H2,1-4H3/q+1
Troxypyrrolium is an inhibitor of the nerve terminal high-affinity sodium- dependent choline uptake system. Troxypyrrolium, a choline uptake inhibitor, reduced but failed to abolish responses of the rat urinary bladder to electrical stimulation at 1-100 Hz although it reduced acetylcholine output during stimulation at 10 Hz to a level similar to that of spontaneous release.
Approval Year
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1668355
Rat nerve stimulation in the presence of troxypyrrolium (20 uM) produced a uniform reduction in the amplitude of all MEPCs with no change in the coefficient of variance of MEPC amplitudes.
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71528
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DTXSID80179228
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3TGW42ZEPG
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admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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24468-02-8
Created by
admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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ACTIVE MOIETY