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Details

Stereochemistry ACHIRAL
Molecular Formula C18H28NO5
Molecular Weight 338.4186
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of TROXYPYRROLIUM

SMILES

CC[N+]2(CCOC(=O)C1=CC(OC)=C(OC)C(OC)=C1)CCCC2

InChI

InChIKey=FYDIOQNEQHPRNW-UHFFFAOYSA-N
InChI=1S/C18H28NO5/c1-5-19(8-6-7-9-19)10-11-24-18(20)14-12-15(21-2)17(23-4)16(13-14)22-3/h12-13H,5-11H2,1-4H3/q+1

HIDE SMILES / InChI
Troxypyrrolium is an inhibitor of the nerve terminal high-affinity sodium- dependent choline uptake system. Troxypyrrolium, a choline uptake inhibitor, reduced but failed to abolish responses of the rat urinary bladder to electrical stimulation at 1-100 Hz although it reduced acetylcholine output during stimulation at 10 Hz to a level similar to that of spontaneous release.

Approval Year

PubMed

PubMed

TitleDatePubMed
The effect of troxypyrrolidinium, a choline uptake inhibitor, on the excitatory innervation of the rat urinary bladder.
1980 Feb 8
Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium.
1991 Dec

Sample Use Guides

In Vitro Use Guide
Rat nerve stimulation in the presence of troxypyrrolium (20 uM) produced a uniform reduction in the amplitude of all MEPCs with no change in the coefficient of variance of MEPC amplitudes.
Name Type Language
TROXYPYRROLIUM
Common Name English
TROXYPYRROLIDINIUM CATION
Common Name English
TROXYPYRROLIDINIUM ION
Common Name English
TROXYPYRROLIDINIUM
Common Name English
TROXYPYRROLIUM CATION
Common Name English
PYRROLIDINIUM, 1-ETHYL-1-(2-((3,4,5-TRIMETHOXYBENZOYL)OXY)ETHYL)-
Systematic Name English
TROXYPYRROLIUM ION
Common Name English
Code System Code Type Description
PUBCHEM
71528
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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EPA CompTox
DTXSID80179228
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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FDA UNII
3TGW42ZEPG
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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CAS
24468-02-8
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
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