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Details

Stereochemistry ACHIRAL
Molecular Formula C18H28NO5
Molecular Weight 338.4186
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 1

SHOW SMILES / InChI
Structure of TROXYPYRROLIUM

SMILES

CC[N+]2(CCOC(=O)C1=CC(OC)=C(OC)C(OC)=C1)CCCC2

InChI

InChIKey=FYDIOQNEQHPRNW-UHFFFAOYSA-N
InChI=1S/C18H28NO5/c1-5-19(8-6-7-9-19)10-11-24-18(20)14-12-15(21-2)17(23-4)16(13-14)22-3/h12-13H,5-11H2,1-4H3/q+1

HIDE SMILES / InChI

Molecular Formula C18H28NO5
Molecular Weight 338.4186
Charge 1
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Troxypyrrolium is an inhibitor of the nerve terminal high-affinity sodium- dependent choline uptake system. Troxypyrrolium, a choline uptake inhibitor, reduced but failed to abolish responses of the rat urinary bladder to electrical stimulation at 1-100 Hz although it reduced acetylcholine output during stimulation at 10 Hz to a level similar to that of spontaneous release.

Approval Year

PubMed

PubMed

TitleDatePubMed
Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium.
1991 Dec

Sample Use Guides

In Vitro Use Guide
Rat nerve stimulation in the presence of troxypyrrolium (20 uM) produced a uniform reduction in the amplitude of all MEPCs with no change in the coefficient of variance of MEPC amplitudes.
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:50:38 GMT 2023
Edited
by admin
on Sat Dec 16 08:50:38 GMT 2023
Record UNII
3TGW42ZEPG
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TROXYPYRROLIUM
Common Name English
TROXYPYRROLIDINIUM CATION
Common Name English
TROXYPYRROLIDINIUM ION
Common Name English
TROXYPYRROLIDINIUM
Common Name English
TROXYPYRROLIUM CATION
Common Name English
PYRROLIDINIUM, 1-ETHYL-1-(2-((3,4,5-TRIMETHOXYBENZOYL)OXY)ETHYL)-
Systematic Name English
TROXYPYRROLIUM ION
Common Name English
Code System Code Type Description
PUBCHEM
71528
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
PRIMARY
EPA CompTox
DTXSID80179228
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
PRIMARY
FDA UNII
3TGW42ZEPG
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
PRIMARY
CAS
24468-02-8
Created by admin on Sat Dec 16 08:50:38 GMT 2023 , Edited by admin on Sat Dec 16 08:50:38 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY