Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H33NO5 |
| Molecular Weight | 319.4369 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COCCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI
InChIKey=TYTARGBBJQKLAJ-QKPAOTATSA-N
InChI=1S/C16H33NO5/c1-22-10-8-6-4-2-3-5-7-9-17-11-14(19)16(21)15(20)13(17)12-18/h13-16,18-21H,2-12H2,1H3/t13-,14+,15-,16-/m1/s1
The immunosugar N-9-methoxynonyldeoxynojirimycin (SP-187, UV-4B) is an inhibitor of both glucosidases I and II. In preclinical studies, it displayed inhibition of dengue and influenza virus infection. The compound developed by Emergent BioSolutions and evaluated in phase 1 clinical trials on healthy subjects.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice. | 2016-03-07 |
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| In vivo therapeutic protection against influenza A (H1N1) oseltamivir-sensitive and resistant viruses by the iminosugar UV-4. | 2015 |
|
| An iminosugar with potent inhibition of dengue virus infection in vivo. | 2013-04 |
|
| Imino sugars that are less toxic but more potent as antivirals, in vitro, compared with N-n-nonyl DNJ. | 2002-09 |
Patents
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Common Name | English | ||
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Preferred Name | English | ||
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Systematic Name | English | ||
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Code | English |
| Code System | Code | Type | Description | ||
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3P161BU63E
Created by
admin on Mon Mar 31 22:10:56 GMT 2025 , Edited by admin on Mon Mar 31 22:10:56 GMT 2025
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503982
Created by
admin on Mon Mar 31 22:10:56 GMT 2025 , Edited by admin on Mon Mar 31 22:10:56 GMT 2025
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615253-61-7
Created by
admin on Mon Mar 31 22:10:56 GMT 2025 , Edited by admin on Mon Mar 31 22:10:56 GMT 2025
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PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
