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Details

Stereochemistry ACHIRAL
Molecular Formula C31H32N4O2
Molecular Weight 492.6114
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BEZITRAMIDE

SMILES

CCC(=O)N1C(=O)N(C2CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=C1C=CC=C5

InChI

InChIKey=FLKWNFFCSSJANB-UHFFFAOYSA-N
InChI=1S/C31H32N4O2/c1-2-29(36)35-28-16-10-9-15-27(28)34(30(35)37)26-17-20-33(21-18-26)22-19-31(23-32,24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-16,26H,2,17-22H2,1H3

HIDE SMILES / InChI

Description

Bezitramide was developed as an orally long-acting analgesic compound and was marketed under the brand name Burgodin. The overdose of this drug caused death that is why it was withdrawn from the market.

Originator

Janssen Pharmaceutica
51

Approval Year

Unknown
139,594

Conditions

ConditionModalityTargetsHighest PhaseProduct
pain
5
 Primary
Withdrawn
Burgodin

PubMed

Patents

JP2007507532A
34

Sample Use Guides

In Vivo Use Guide
5 mg
Route of Administration: Oral
ACTIVE MOIETY
Structure of BEZITRAMIDE
METABOLITE ACTIVE (PRODRUG)
Structure of DESPROPIONYLBEZITRAMIDE
SALT/SOLVATE (PARENT)
Structure of BETAPRODINE HYDROCHLORIDE
NIH
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