Stereochemistry | ABSOLUTE |
Molecular Formula | C8H4O12Sb2.2Na |
Molecular Weight | 581.61 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]C(=O)[C@@H]1O[Sb]2O[C@H]([C@@H](O[Sb]3O[C@H]1C(=O)O3)C([O-])=O)C(=O)O2
InChI
InChIKey=UZVPADYOEPQJSP-SOMOIXMJSA-J
InChI=1S/2C4H4O6.2Na.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;/h2*1-2H,(H,7,8)(H,9,10);;;;/q2*-2;2*+1;2*+3/p-4/t2*1-,2-;;;;/m11..../s1
Antimony sodium tartrate (stibophen) is a trivalent antimony compound having the same actions and uses as the potassium tartrate but more water-soluble and less irritant when injected. Antimony sodium tartrate has been used in the treatment of Schistosomiasis since 1918. It is a toxic drug and may cause unpleasant side-effects.This drug is now rarely used in the therapy of leishmaniasis, as drugs which are much better tolerated are available
Approval Year
PubMed
Patents
Sample Use Guides
Schistosomiasis : For adults two grains of sodium antimony tartrate were dissolved in 20 c.c. of 5 per cent. glucose,
and slowly injected intravenously through a 16-gauge needle--children were given doses according
to their weights, taking 60 kg as adult weight.
Route of Administration:
Intravenous