Tetrabarbital

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H20N2O3
Molecular Weight	240.2988
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of Tetrabarbital

Structure Search

SMILES

CCCC(CC)C1(CC)C(=O)NC(=O)NC1=O

InChI

InChIKey=ZLUNGGZJSQDFPH-UHFFFAOYSA-N

InChI=1S/C12H20N2O3/c1-4-7-8(5-2)12(6-3)9(15)13-11(17)14-10(12)16/h8H,4-7H2,1-3H3,(H2,13,14,15,16,17)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13603366

Tetrabarbital is a barbituric acid derivative patented by Eli Lilly and Co. as a central nervous system depressant. In chloralosed dogs, intravenous Tetrabarbital 2.5-10 mg/kg, accelerated the heartbeat and lowered the carotid pressure.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Pharmacodynamic study of two barbituric acid derivatives: tetrabarbital and tetrathiobarbital].	1958	13603366

Patents

Patents

Name

Type

Language

Tetrabarbital

Official Name

English

TETRABARBITAL [MI]

Preferred Name

English

tetrabarbital [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C67084

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Code System Code Type Description

EPA CompTox

DTXSID50861623

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CAS

76-23-3

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INN

364

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EVMPD

SUB10938MIG

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ECHA (EC/EINECS)

200-946-6

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FDA UNII

3K441526FO

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MERCK INDEX

m957

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Merck Index

WIKIPEDIA

Tetrabarbital

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NCI_THESAURUS

C74383

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PUBCHEM

101534

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SMS_ID

100000082716

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ChEMBL

CHEMBL2107053

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DRUG CENTRAL

3840

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ACTIVE MOIETY


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