VALYLTRYPTOPHAN

Possibly Marketed Outside US

CC(C)[C@H](N)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

InChIKey=LZDNBBYBDGBADK-KBPBESRZSA-N

InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1

Conditions

Condition	Modality	Targets	Highest Phase	Product
Skin Aging 3 Sources: https://www.drugs.com/otc/472121/tonymoly-intense-care-gold-syn-ake-wrinkle-cream.html	Inactive ingredient		Approved 8583	TONYMOLY Intense Care Gold Syn-Ake Wrinkle Cream Approved Use Unknown
Skin Care 16 Sources: https://www.drugs.com/otc/809949/eye-contour-anti-puffiness-and-dark-circles-eye-correct.html	Inactive ingredient		Approved 8583	EYE CONTOUR ANTI-PUFFINESS AND DARK CIRCLES. EYE CORRECT Approved Use Unknown

Overview

CYP3A4	CYP2C9	CYP2D6	hERG
inhibitor 2252 activator 150

Other Inhibitor	Other Substrate	Other Inducer
OATP1B3 961 PEPT1 27 OATP1B1 1079

Drug as perpetrator

Target	Modality	Activity
CYP3A4 2633	activator 342 Sources: https://pubchem.ncbi.nlm.nih.gov/bioassay/885#sid=26749903	no
CYP3A4 2633	inhibitor 4027 Sources: https://pubchem.ncbi.nlm.nih.gov/bioassay/884#sid=26749903	no
PEPT1 29	activator 342 Sources: https://pubmed.ncbi.nlm.nih.gov/16759105/	yes [EC50 40 uM]
PEPT1 29	inhibitor 4027 Sources: https://pubmed.ncbi.nlm.nih.gov/16759105/	yes [IC50 100 uM]
OATP1B1 1095	inhibitor 4027 Sources: https://pubmed.ncbi.nlm.nih.gov/23571415/	yes [Inhibition 10 uM]
OATP1B3 970	inhibitor 4027 Sources: https://pubmed.ncbi.nlm.nih.gov/23571415/	yes [Inhibition 10 uM]

Patents

Name

Type

Language

VALYLTRYPTOPHAN

Systematic Name

English

DIPEPTIDE-2

Preferred Name

English

L-TRYPTOPHAN, L-VALYL-

Systematic Name

English

DIPEPTIDE VW

Brand Name

English

VAL-TRP

Common Name

English

L-VALYL-L-TRYPTOPHAN

Systematic Name

English

DIPEPTIDE VAL-TRP

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C247