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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5ClO
Molecular Weight 128.556
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARACHLOROPHENOL

SMILES

OC1=CC=C(Cl)C=C1

InChI

InChIKey=WXNZTHHGJRFXKQ-UHFFFAOYSA-N
InChI=1S/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8H

HIDE SMILES / InChI

Description

Since 4-chlorophenol is caustic, toxic, and fairly difficult to dispense because it has s melting point of 43% it is convenient to run the reaction of synthesis of p-chlorophenoxyacetic acid for preparation of a synthetic plant hormone using a stock solution that is 1.0 M sodium 4-chlorophenolate and 2.5 M sodium hydroxide. Addition of ehloroacetic acid (CI-CH2C02H) to this solution gives the chloroacetate anion (VIII). sodium 4-chlorophenolate is a local antibacterial agent in root canal therapy. It is also used as topical antiseptic, formerly used as topical antiseptic in ointments.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown
Curative
Endotine

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Dental
In Vitro Use Guide
0.01 mM of camphorated parachlorophenol (parachlorophenol) inhibited periodontal ligament cells proliferation, as shown by [3H]thymidine incorporation.