Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C16H21N.ClH |
| Molecular Weight | 263.806 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.[H][C@@]12CC3=CC=CC=C3[C@]4(CCCC[C@@]14[H])CCN2
InChI
InChIKey=UTTZKIWMKFVYCK-CLUYDPBTSA-N
InChI=1S/C16H21N.ClH/c1-2-6-13-12(5-1)11-15-14-7-3-4-8-16(13,14)9-10-17-15;/h1-2,5-6,14-15,17H,3-4,7-11H2;1H/t14-,15+,16-;/m0./s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Anticonvulsant effects of new morphinan derivatives. | 2001 Jul 9 |
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| Morphine-6beta-glucuronide and morphine-3-glucuronide, opioid receptor agonists with different potencies. | 2001 Nov 1 |
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| New dimeric morphine from opium poppy (Papaver somuniferum) and its physiological function. | 2003 Jul |
|
| New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice. | 2003 Mar 7 |
|
| Electrospray tandem mass spectrometric investigations of morphinans. | 2003 Nov |
|
| 1,2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway. | 2004 Apr |
|
| 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. | 2004 Jan 1 |
|
| A new group of highly active analgesic of the morphinan family. | 2004 Jan-Feb |
|
| A role for intra- and intercellular translocation in natural product biosynthesis. | 2005 Jun |
|
| Opium Poppy (Papaver somniferum). | 2006 |
|
| Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. | 2006 Oct |
|
| Non-competitive inhibitory activities of morphinan and morphine derivatives at the alpha 3 beta 4 Neuronal nicotinic acetylcholine receptor determined using nonlinear chromatography and chemometric techniques. | 2006 Sep |
|
| Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. | 2007 Jan |
|
| Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. | 2008 |
|
| Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy. | 2008 Jan |
|
| The presence of endogenous morphine signaling in animals. | 2008 Oct |
|
| Synthesis of a stable iminium salt and propellane derivatives. | 2008 Oct 17 |
|
| Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. | 2008 Sep |
|
| 7α-Methoxy-carbonyl-6,7,8,14-tetra-hydro-6,14-endo-ethenothebaine. | 2009 Mar 25 |
|
| Synthesis and SAR study of opioid receptor ligands: mono- and bis-indolomorphinans. | 2009 Oct |
|
| Biochemistry and occurrence of o-demethylation in plant metabolism. | 2010 |
|
| Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica. | 2010 |
|
| Morphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors. | 2010 Jul 15 |
|
| Hasubanan alkaloids with delta-opioid binding affinity from the aerial parts of Stephania japonica. | 2010 May 28 |
|
| Interactive effects of endogenous morphine, nitric oxide, and ethanol on mitochondrial processes. | 2010 Oct |
Patents
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| Code System | Code | Type | Description | ||
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20678913
Created by
admin on Sat Dec 16 01:11:45 GMT 2023 , Edited by admin on Sat Dec 16 01:11:45 GMT 2023
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3BR0Y870P7
Created by
admin on Sat Dec 16 01:11:45 GMT 2023 , Edited by admin on Sat Dec 16 01:11:45 GMT 2023
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1071557-77-1
Created by
admin on Sat Dec 16 01:11:45 GMT 2023 , Edited by admin on Sat Dec 16 01:11:45 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
