Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C16H21N |
| Molecular Weight | 227.3446 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC3=CC=CC=C3[C@]4(CCCC[C@@]14[H])CCN2
InChI
InChIKey=INAXVFBXDYWQFN-XHSDSOJGSA-N
InChI=1S/C16H21N/c1-2-6-13-12(5-1)11-15-14-7-3-4-8-16(13,14)9-10-17-15/h1-2,5-6,14-15,17H,3-4,7-11H2/t14-,15+,16-/m0/s1
| Molecular Formula | C16H21N |
| Molecular Weight | 227.3446 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Alkaloid biosynthesis in Papaver sp. cells in culture and during organogenesis. | 2001 May-Jun |
|
| Morphinan derivatives--A review of the recent patent literature. | 2003 Feb |
|
| New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice. | 2003 Mar 7 |
|
| Electrospray tandem mass spectrometric investigations of morphinans. | 2003 Nov |
|
| 1,2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway. | 2004 Apr |
|
| Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots. | 2004 Dec |
|
| Na+ modulation, inverse agonism, and anorectic potency of 4-phenylpiperidine opioid antagonists. | 2004 Jun 28 |
|
| Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone]. | 2004 Mar 11 |
|
| 6-oxo-morphinane oximes: pharmacology, chemistry and analytical application. | 2004 Oct |
|
| Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence. | 2004 Oct |
|
| Characterization of the complex morphinan derivative BU72 as a high efficacy, long-lasting mu-opioid receptor agonist. | 2004 Sep 19 |
|
| Protective effect of dextromethorphan against endotoxic shock in mice. | 2005 Jan 15 |
|
| A role for intra- and intercellular translocation in natural product biosynthesis. | 2005 Jun |
|
| Opium Poppy (Papaver somniferum). | 2006 |
|
| Total synthesis of (+/-)-morphine. | 2006 Nov 9 |
|
| QSAR study on the antinociceptive activity of some morphinans. | 2007 Jul |
|
| In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors. | 2007 Jun 15 |
|
| Levorphanol: the forgotten opioid. | 2007 Mar |
|
| High-affinity carbamate analogues of morphinan at opioid receptors. | 2007 Mar 15 |
|
| Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. | 2008 |
|
| Morphinane alkaloid dimers from Sinomenium acutum. | 2008 Jan |
|
| Concise synthesis of dimemorfan (DF) starting from 3-hydroxymorphinan (3-HM). | 2008 Jul |
|
| Isolation and antimalarial activity of new morphinan alkaloids on Plasmodium yoelii liver stage. | 2008 Jun 1 |
|
| Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2. | 2008 Mar 21 |
|
| Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. | 2008 Sep |
|
| Recent developments in the chemistry of thebaine and its transformation products as pharmacological targets. | 2009 |
|
| Bisbenzylisoquinoline alkaloids from Cocculus pendulus. | 2009 |
|
| Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands. | 2009 Dec 10 |
|
| 7α-Methoxy-carbonyl-6,7,8,14-tetra-hydro-6,14-endo-ethenothebaine. | 2009 Mar 25 |
|
| Biochemistry and occurrence of o-demethylation in plant metabolism. | 2010 |
|
| Biological indications of a novel "short" µ opiate receptor in domestic chicken. | 2010 Aug 30 |
|
| Interactive effects of endogenous morphine, nitric oxide, and ethanol on mitochondrial processes. | 2010 Oct |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 01:12:19 GMT 2023
by
admin
on
Sat Dec 16 01:12:19 GMT 2023
|
| Record UNII |
OJ66WL736G
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Code System | Code | Type | Description | ||
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1215192-09-8
Created by
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OJ66WL736G
Created by
admin on Sat Dec 16 01:12:19 GMT 2023 , Edited by admin on Sat Dec 16 01:12:19 GMT 2023
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6857497
Created by
admin on Sat Dec 16 01:12:19 GMT 2023 , Edited by admin on Sat Dec 16 01:12:19 GMT 2023
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Morphinan
Created by
admin on Sat Dec 16 01:12:19 GMT 2023 , Edited by admin on Sat Dec 16 01:12:19 GMT 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT | |||
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ENANTIOMER -> RACEMATE |
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