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Details

Stereochemistry ACHIRAL
Molecular Formula C23H27N3O.ClH
Molecular Weight 397.941
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRENOXDIAZINE HYDROCHLORIDE

SMILES

Cl.C(CC1=NC(CC(C2=CC=CC=C2)C3=CC=CC=C3)=NO1)N4CCCCC4

InChI

InChIKey=ONTOFAWPPHNLML-UHFFFAOYSA-N
InChI=1S/C23H27N3O.ClH/c1-4-10-19(11-5-1)21(20-12-6-2-7-13-20)18-22-24-23(27-25-22)14-17-26-15-8-3-9-16-26;/h1-2,4-7,10-13,21H,3,8-9,14-18H2;1H

HIDE SMILES / InChI

Description

Prenoxdiazine under the brand name Libexin is used as an antitussive agent. It was shown, that the use of this drug for pregnant women with an unproductive cough could be beneficial.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1430
PubMed

PubMed

TitleDatePubMed
[Study on the antitussive effect of Libexin in clinical practice].
1966 Jul 24
[Report on a multi-center study of a new prenoxdiazine antitussive agent].
1973 Jun 10
No teratogenic effect of prenoxdiazine: a population-based case-control study.
2007 Mar
Patents

Patents

20050002865
228
20070224187
4
20090317473
3

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
Name Type Language
PRENOXDIAZINE HYDROCHLORIDE
MI  
Common Name English
TIBEXIN
Brand Name English
LIBEXIN
Brand Name English
HK-256
Code English
PRENOXDIAZINE HYDROCHLORIDE [MI]
Common Name English
PIPERIDINE, 1-(2-(3-(2,2-DIPHENYLETHYL)-1,2,4-OXADIAZOL-5-YL)ETHYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
LOMAPECT
Common Name English
Prenoxdiazin hydrochloride [WHO-DD]
Common Name English
PRENOXDIAZIN HYDROCHLORIDE
WHO-DD  
Common Name English
LIBEKSIN
Brand Name English
Code System Code Type Description
WIKIPEDIA
Libexin
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
ECHA (EC/EINECS)
213-567-6
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
CAS
982-43-4
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
MERCK INDEX
m9124
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID00243511
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
PUBCHEM
120507
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
EVMPD
SUB15009MIG
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
SMS_ID
100000078851
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
FDA UNII
390WW7V7MZ
Created by admin on Sat Dec 16 06:08:03 GMT 2023 , Edited by admin on Sat Dec 16 06:08:03 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of PRENOXDIAZINE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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