PRENOXDIAZINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H27N3O.ClH
Molecular Weight	397.941
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PRENOXDIAZINE HYDROCHLORIDE

Structure Search

SMILES

Cl.C(CC1=NC(CC(C2=CC=CC=C2)C3=CC=CC=C3)=NO1)N4CCCCC4

InChI

InChIKey=ONTOFAWPPHNLML-UHFFFAOYSA-N

InChI=1S/C23H27N3O.ClH/c1-4-10-19(11-5-1)21(20-12-6-2-7-13-20)18-22-24-23(27-25-22)14-17-26-15-8-3-9-16-26;/h1-2,4-7,10-13,21H,3,8-9,14-18H2;1H

HIDE SMILES / InChI

Molecular Formula	C23H27N3O
Molecular Weight	361.48
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5968420 | https://www.ncbi.nlm.nih.gov/pubmed/2667194 | https://www.ncbi.nlm.nih.gov/pubmed/17300686

Prenoxdiazine under the brand name Libexin is used as an antitussive agent. It was shown, that the use of this drug for pregnant women with an unproductive cough could be beneficial.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
phagocytosis 3 Target ID: GO:0006909 Sources: https://www.ncbi.nlm.nih.gov/pubmed/340236	Activator 1430

PubMed

Title	Date	PubMed
[Study on the antitussive effect of Libexin in clinical practice].	1966 Jul 24	5968420
[Report on a multi-center study of a new prenoxdiazine antitussive agent].	1973 Jun 10	4576446
No teratogenic effect of prenoxdiazine: a population-based case-control study.	2007 Mar	17300686

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 06:08:03 GMT 2023` Edited by `admin` on `Sat Dec 16 06:08:03 GMT 2023`
Record UNII	390WW7V7MZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRENOXDIAZINE HYDROCHLORIDE

Common Name

English

TIBEXIN

Brand Name

English

LIBEXIN

Brand Name

English

HK-256

Code

English

PRENOXDIAZINE HYDROCHLORIDE [MI]

Common Name

English

PIPERIDINE, 1-(2-(3-(2,2-DIPHENYLETHYL)-1,2,4-OXADIAZOL-5-YL)ETHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

LOMAPECT

Common Name

English

Prenoxdiazin hydrochloride [WHO-DD]

Common Name

English

PRENOXDIAZIN HYDROCHLORIDE

Common Name

English

LIBEKSIN

Brand Name

English

Code System Code Type Description

WIKIPEDIA

Libexin