Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C16H14O4 |
| Molecular Weight | 270.28 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(O)=CC=C1\C=C\C(=O)C2=CC=C(O)C=C2
InChI
InChIKey=QJKMIJNRNRLQSS-WEVVVXLNSA-N
InChI=1S/C16H14O4/c1-20-16-10-14(18)8-4-12(16)5-9-15(19)11-2-6-13(17)7-3-11/h2-10,17-18H,1H3/b9-5+
Echinatin is a component of Glycyrrhiza echinata, which have been used for years in Chinese traditional medicine. It displays antioxidant properties and anti-inflammatory activities. Echinatin exerts a protective effect against I/R-induced myocardial injury on hearts (as shown on the isolated rat hearts).
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cardioprotection provided by Echinatin against ischemia/reperfusion in isolated rat hearts. | 2016-05-31 |
|
| Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines. | 2000-08-23 |
|
| The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction. | 1982-11 |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27246834
The hearts of the rats in the treatment groups were stabilized for 30 min and then treated with a Krebs-Henseleit buffer solution containing Echinatin (0.1, 0.5, and 2.5 ug/mL). Global ischemia and reperfusion were established for 45 min.
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SUBSTANCE RECORD