Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H15NO2 |
Molecular Weight | 157.2102 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC[C@H]1CC[C@H](CC1)C(O)=O
InChI
InChIKey=GYDJEQRTZSCIOI-KNVOCYPGSA-N
InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7+
DescriptionSources: https://www.trc-canada.com/product-detail/?T714502
Sources: https://www.trc-canada.com/product-detail/?T714502
cis-Tranexamic acid blocks the plasminogen, and thus possesses antifibrinolytic properties.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P00747 Gene ID: 5340.0 Gene Symbol: PLG Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/473126 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/473126
When human plasma was mixed with 50 units of urokinase and clotted with thrombin in the presence of S-2251, the hydrolysis of S-2251 in the clot was higher than that in the plasma. The addition of 6-aminohexanoic acid or cis-AMCHA (cis-Tranexamic Acid) showed changes in the rate of plasminogen activation similar to that shown in the presence of tranexamic acid. 1 mM of cis-AMCHA and 6-aminohexanoic acid totally inhibited clot lysis. The presence of 1 mM of these ω-aminoacids remarkably increased the activation of plasminogen by urokinase, but no clot lysis was observed.
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5526
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m11000
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1197-17-7
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37YD696II6
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SUBSTANCE RECORD