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Details

Stereochemistry ACHIRAL
Molecular Formula C36H36N2O3
Molecular Weight 544.6826
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FETOXYLATE

SMILES

O=C(OCCOC1=CC=CC=C1)C2(CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=CC=CC=C5

InChI

InChIKey=KISQOVVPIHYLRD-UHFFFAOYSA-N
InChI=1S/C36H36N2O3/c37-29-36(31-15-7-2-8-16-31,32-17-9-3-10-18-32)23-26-38-24-21-35(22-25-38,30-13-5-1-6-14-30)34(39)41-28-27-40-33-19-11-4-12-20-33/h1-20H,21-28H2

HIDE SMILES / InChI
FETOXYLATE, a phenoxyethyl ester of diphenoxylate, is an opioid receptor agonist. It is used as antidiarrheal.

Approval Year

PubMed

PubMed

TitleDatePubMed
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.
1984 Dec

Sample Use Guides

In Vitro Use Guide
The antidiarrheal opiates loperamide, fluperamide, diphenoxylate, and fetoxylate inhibited binding of [3H]nitrendipine to membranes from guinea-pig cerebral cortex with Ki values of 0.5 to 10 microM.
Name Type Language
FETOXYLATE
Common Name English
4-PIPERIDINECARBOXYLIC ACID, 1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PHENYL-, 2-PHENOXYETHYL ESTER
Common Name English
Fetoxilate [WHO-DD]
Common Name English
2-PHENOXYETHYL 1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PHENYLISONIPECOTATE
Systematic Name English
FETOXILATE
INN   WHO-DD  
INN  
Official Name English
fetoxilate [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C266
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2110871
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID10202391
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
INN
2586
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
CAS
54063-45-5
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
EVMPD
SUB07616MIG
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
FDA UNII
3791SET69Y
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
SMS_ID
100000080963
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
NCI_THESAURUS
C81494
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY
PUBCHEM
32027
Created by admin on Sat Dec 16 16:54:42 GMT 2023 , Edited by admin on Sat Dec 16 16:54:42 GMT 2023
PRIMARY