U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula 2C6H7O6.Mn
Molecular Weight 405.1704
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MANGANESE ASCORBATE

SMILES

[Mn++].[H][C@@]1(OC(=O)C([O-])=C1O)[C@@H](O)CO.[H][C@@]2(OC(=O)C([O-])=C2O)[C@@H](O)CO

InChI

InChIKey=RSYSVNVHLXTDIR-ZZMNMWMASA-L
InChI=1S/2C6H8O6.Mn/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including http://google.com/patents/WO1992012714 | https://www.google.com/patents/WO2005082386A3

Manganese is a mineral salt that is found in several foods including nuts, legumes, seeds, tea, whole grains, and leafy green vegetables. It is considered an essential nutrient, because the body requires it to function properly. Manganese is used for prevention and treatment of manganese deficiency, a condition in which the body doesn’t have enough manganese. It is also used for weak bones (osteoporosis), a type of “tired blood” (anemia), and symptoms of premenstrual syndrome (PMS). Manganese is sometimes included with chondroitin sulfate and glucosamine hydrochloride in multi-ingredient products promoted for osteoarthritis.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.
2001 Feb
Patents

Patents

Sample Use Guides

Osteoporosis: 5 mg of manganese per day combined with 1000 mg of elemental calcium, 15 mg of zinc, and 2.5 mg of copper. The daily Adequate Intake (AI) levels for manganese are: infants birth to 6 months, 3 mcg; 7 to 12 months, 600 mcg; children 1 to 3 years, 1.2 mg; 4 to 8 years 1.5 mg; boys 9 to 13 years, 1.9 mg; boys 14 to 18 years, 2.2 mg; girls 9 to 18 years, 1.6 mg; men age 19 and older, 2.3 mg; women 19 and older, 1.8 mg; pregnant women age 14 to 50, 2 mg; breastfeeding women, 2.6 mg.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
MANGANESE ASCORBATE
WHO-DD  
Common Name English
ASCORBIC ACID MANGANESE
Brand Name English
MANGANESE(2+) 5-((1R)-1,2-DIHYDROXYETHYL)-4-HYDROXY-2-OXO-2,5-DIHYDRO-3-FURANOLATE 5-((1S)-1,2-DIHYDROXYETHYL)-4-HYDROXY-2-OXO-2,5-DIHYDRO-3-FURANOLATE (1:1:1)
Systematic Name English
L-ASCORBIC ACID, MANGANESE SALT
Common Name English
ASCORBATE MANGANESE
Common Name English
COSAMIN DS
Brand Name English
Manganese ascorbate [WHO-DD]
Common Name English
Classification Tree Code System Code
DSLD 3676 (Number of products:1)
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
Code System Code Type Description
SMS_ID
100000076486
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
EVMPD
SUB14467MIG
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID001020116
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
FDA UNII
332B7O278V
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
CAS
16351-10-3
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
DAILYMED
332B7O278V
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
PUBCHEM
90479050
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY
RXCUI
1144960
Created by admin on Sat Dec 16 02:06:42 GMT 2023 , Edited by admin on Sat Dec 16 02:06:42 GMT 2023
PRIMARY