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Details

Stereochemistry ACHIRAL
Molecular Formula Mn
Molecular Weight 54.938
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MANGANESE

SMILES

[Mn]

InChI

InChIKey=PWHULOQIROXLJO-UHFFFAOYSA-N
InChI=1S/Mn

HIDE SMILES / InChI

Molecular Formula Mn
Molecular Weight 54.938
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Environmental factors in western Pacific foci of ALS and a possible pathogenetic role of aluminum (Al) in motor neuron degeneration].
1991 Dec
The kinetics of inhibition of Vigna catjang cotyledon and buffalo liver arginase by L-proline and branched-chain amino acids.
2006 Dec
Cytogenetic effects of a mixture of selected metals following subchronic exposure through drinking water in male rats.
2006 Dec
Environmental stressors (salinity, heavy metals, H2O2) modulate expression of glutathione reductase (GR) gene from the intertidal copepod Tigriopus japonicus.
2006 Dec 1
Activation of MAP kinases by hexavalent chromium, manganese and nickel in human lung epithelial cells.
2006 Dec 1
Manganese is highly effective in protecting cells from cadmium intoxication.
2006 Dec 8
Structural insights into the mechanism of PEPCK catalysis.
2006 Jul 11
p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.
2006 Jul 12
Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase.
2006 Jul 28
SOD2-deficiency sideroblastic anemia and red blood cell oxidative stress.
2006 Jul-Aug
Lactoferrin and bone; structure-activity relationships.
2006 Jun
Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes.
2006 Jun 20
Upregulation of DMT1 expression in choroidal epithelia of the blood-CSF barrier following manganese exposure in vitro.
2006 Jun 30
Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure.
2006 Nov
TAK1-binding protein 1 is a pseudophosphatase.
2006 Nov 1
Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87).
2006 Oct
Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis.
2006 Oct
The specific, submicromolar-Km ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn2+ as activating cation and increase in Km for ADP-ribose, both elicited by H2O2.
2006 Oct
Divalent-metal-dependent nucleolytic activity of Cu, Zn superoxide dismutase.
2006 Oct
Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics.
2006 Oct 3
Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain.
2006 Sep
Brain accumulation and toxicity of Mn(II) and Mn(III) exposures.
2006 Sep
Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese.
2006 Summer
Putative proteins involved in manganese transport across the blood-brain barrier.
2007 Apr
KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart.
2007 Apr
Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding.
2007 Dec 1
Induction of metallothionein by manganese is completely dependent on interleukin-6 production.
2007 Feb
Amino acid and manganese supplementation modulates the glycosylation state of erythropoietin in a CHO culture system.
2007 Feb 15
Olfactory uptake of manganese requires DMT1 and is enhanced by anemia.
2007 Jan
Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain.
2007 Jan
Manganese induces oxidative impairment in cultured rat astrocytes.
2007 Jul
The Nrf2 transcription factor contributes to the induction of alpha-class GST isoenzymes in liver of acute cadmium or manganese intoxicated rats: comparison with the toxic effect on NAD(P)H:quinone reductase.
2007 Jul 31
Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells.
2007 Jun
Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
2007 Jun
Subchronic inhalation of soluble manganese induces expression of hypoxia-associated angiogenic genes in adult mouse lungs.
2007 Jun 1
Effect of manganese supplementation and source on carcass traits, meat quality, and lipid oxidation in broilers.
2007 Mar
Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells.
2007 May
Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects.
2007 Nov
Role of Ca2+-independent phospholipase A2 and store-operated pathway in urocortin-induced vasodilatation of rat coronary artery.
2007 Nov 26
Characterization and distribution of the selected metals in the scalp hair of cancer patients in comparison with normal donors.
2007 Sep
Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus.
2007 Sep
Inhibition of lipopolysaccharide activation of Kupffer cells by transition metals.
2008 Aug
Mitochondrial-mediated apoptosis in neural stem cells exposed to manganese.
2008 Feb
The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells.
2008 Feb 15
The role of dopamine transporter in selective toxicity of manganese and rotenone.
2008 Feb 28
Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways.
2008 Jul
Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates.
2008 Jun
Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.
2008 Mar-Apr
Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging.
2008 May
Manganese cell labeling of murine hepatocytes using manganese(III)-transferrin.
2008 May-Jun
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 05:23:40 UTC 2021
Edited
by admin
on Sat Jun 26 05:23:40 UTC 2021
Record UNII
42Z2K6ZL8P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MANGANESE
HSDB   MART.   MI   VANDF   WHO-DD  
Systematic Name English
MN
Common Name English
MANGANESE [VANDF]
Common Name English
MANGANESE [WHO-DD]
Common Name English
MANGANUM METALLICUM
HPUS  
Common Name English
MANGANESE [HSDB]
Common Name English
MANGANESE [MI]
Common Name English
MANGANESE [MART.]
Common Name English
MANGANUM METALLICUM [HPUS]
Common Name English
Classification Tree Code System Code
LIVERTOX 580
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
NCI_THESAURUS C637
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
NCI_THESAURUS C896
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
DSLD 252 (Number of products:6106)
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
Code System Code Type Description
EVMPD
SUB14477MIG
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
ALTERNATIVE
CAS
7439-96-5
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
MESH
D008345
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
DRUG BANK
DB06757
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
RXCUI
6623
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY RxNorm
ECHA (EC/EINECS)
231-105-1
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
FDA UNII
42Z2K6ZL8P
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
HSDB
550
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
EVMPD
SUB14466MIG
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
NCI_THESAURUS
C68266
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
PUBCHEM
23930
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
MERCK INDEX
M7058
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY Merck Index
EPA CompTox
7439-96-5
Created by admin on Sat Jun 26 05:23:40 UTC 2021 , Edited by admin on Sat Jun 26 05:23:40 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
Nutritional value per 100 g (3.5 oz) - 0.21 mg (10%)
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY