Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | Mn |
| Molecular Weight | 54.938 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Mn]
InChI
InChIKey=PWHULOQIROXLJO-UHFFFAOYSA-N
InChI=1S/Mn
| Molecular Formula | Mn |
| Molecular Weight | 54.938 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Environmental factors in western Pacific foci of ALS and a possible pathogenetic role of aluminum (Al) in motor neuron degeneration]. | 1991 Dec |
|
| The kinetics of inhibition of Vigna catjang cotyledon and buffalo liver arginase by L-proline and branched-chain amino acids. | 2006 Dec |
|
| Cytogenetic effects of a mixture of selected metals following subchronic exposure through drinking water in male rats. | 2006 Dec |
|
| Environmental stressors (salinity, heavy metals, H2O2) modulate expression of glutathione reductase (GR) gene from the intertidal copepod Tigriopus japonicus. | 2006 Dec 1 |
|
| Activation of MAP kinases by hexavalent chromium, manganese and nickel in human lung epithelial cells. | 2006 Dec 1 |
|
| Manganese is highly effective in protecting cells from cadmium intoxication. | 2006 Dec 8 |
|
| Structural insights into the mechanism of PEPCK catalysis. | 2006 Jul 11 |
|
| p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells. | 2006 Jul 12 |
|
| Identification of Mn2+-binding aspartates from alpha, beta, and gamma subunits of human NAD-dependent isocitrate dehydrogenase. | 2006 Jul 28 |
|
| SOD2-deficiency sideroblastic anemia and red blood cell oxidative stress. | 2006 Jul-Aug |
|
| Lactoferrin and bone; structure-activity relationships. | 2006 Jun |
|
| Evidence for a two-step mechanism involved in the formation of covalent HC x TSG-6 complexes. | 2006 Jun 20 |
|
| Upregulation of DMT1 expression in choroidal epithelia of the blood-CSF barrier following manganese exposure in vitro. | 2006 Jun 30 |
|
| Reversible Parkinsonism and T1W pallidal hyperintensities in acute liver failure. | 2006 Nov |
|
| TAK1-binding protein 1 is a pseudophosphatase. | 2006 Nov 1 |
|
| Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87). | 2006 Oct |
|
| Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis. | 2006 Oct |
|
| The specific, submicromolar-Km ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn2+ as activating cation and increase in Km for ADP-ribose, both elicited by H2O2. | 2006 Oct |
|
| Divalent-metal-dependent nucleolytic activity of Cu, Zn superoxide dismutase. | 2006 Oct |
|
| Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics. | 2006 Oct 3 |
|
| Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain. | 2006 Sep |
|
| Brain accumulation and toxicity of Mn(II) and Mn(III) exposures. | 2006 Sep |
|
| Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese. | 2006 Summer |
|
| Putative proteins involved in manganese transport across the blood-brain barrier. | 2007 Apr |
|
| KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart. | 2007 Apr |
|
| Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding. | 2007 Dec 1 |
|
| Induction of metallothionein by manganese is completely dependent on interleukin-6 production. | 2007 Feb |
|
| Amino acid and manganese supplementation modulates the glycosylation state of erythropoietin in a CHO culture system. | 2007 Feb 15 |
|
| Olfactory uptake of manganese requires DMT1 and is enhanced by anemia. | 2007 Jan |
|
| Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain. | 2007 Jan |
|
| Manganese induces oxidative impairment in cultured rat astrocytes. | 2007 Jul |
|
| The Nrf2 transcription factor contributes to the induction of alpha-class GST isoenzymes in liver of acute cadmium or manganese intoxicated rats: comparison with the toxic effect on NAD(P)H:quinone reductase. | 2007 Jul 31 |
|
| Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells. | 2007 Jun |
|
| Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes. | 2007 Jun |
|
| Subchronic inhalation of soluble manganese induces expression of hypoxia-associated angiogenic genes in adult mouse lungs. | 2007 Jun 1 |
|
| Effect of manganese supplementation and source on carcass traits, meat quality, and lipid oxidation in broilers. | 2007 Mar |
|
| Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells. | 2007 May |
|
| Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects. | 2007 Nov |
|
| Role of Ca2+-independent phospholipase A2 and store-operated pathway in urocortin-induced vasodilatation of rat coronary artery. | 2007 Nov 26 |
|
| Characterization and distribution of the selected metals in the scalp hair of cancer patients in comparison with normal donors. | 2007 Sep |
|
| Effects of manganese complexes of curcumin and diacetylcurcumin on kainic acid-induced neurotoxic responses in the rat hippocampus. | 2007 Sep |
|
| Inhibition of lipopolysaccharide activation of Kupffer cells by transition metals. | 2008 Aug |
|
| Mitochondrial-mediated apoptosis in neural stem cells exposed to manganese. | 2008 Feb |
|
| The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells. | 2008 Feb 15 |
|
| The role of dopamine transporter in selective toxicity of manganese and rotenone. | 2008 Feb 28 |
|
| Manganese potentiates nuclear factor-kappaB-dependent expression of nitric oxide synthase 2 in astrocytes by activating soluble guanylate cyclase and extracellular responsive kinase signaling pathways. | 2008 Jul |
|
| Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. | 2008 Jun |
|
| Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis. | 2008 Mar-Apr |
|
| Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging. | 2008 May |
|
| Manganese cell labeling of murine hepatocytes using manganese(III)-transferrin. | 2008 May-Jun |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 05:23:40 UTC 2021
by
admin
on
Sat Jun 26 05:23:40 UTC 2021
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| Record UNII |
42Z2K6ZL8P
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| Record Status |
Validated (UNII)
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| Record Version |
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LIVERTOX |
580
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NCI_THESAURUS |
C637
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NCI_THESAURUS |
C896
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DSLD |
252 (Number of products:6106)
Created by
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| Code System | Code | Type | Description | ||
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SUB14477MIG
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ALTERNATIVE | |||
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7439-96-5
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D008345
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DB06757
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6623
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231-105-1
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42Z2K6ZL8P
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550
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SUB14466MIG
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C68266
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23930
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M7058
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PRIMARY | Merck Index | ||
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7439-96-5
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| Related Record | Type | Details | ||
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PARENT -> CONSTITUENT ALWAYS PRESENT |
Nutritional value per 100 g (3.5 oz) - 0.21 mg (10%)
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
