Details
Stereochemistry | RACEMIC |
Molecular Formula | C17H17NO2 |
Molecular Weight | 267.3224 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CCC3=C(C=C(O)C(O)=C3)[C@]1([H])C4=C(CN2)C=CC=C4
InChI
InChIKey=BGOQGUHWXBGXJW-YOEHRIQHSA-N
InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m0/s1
Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. Dihydrexidine was shown to stimulate cyclic AMP synthesis just as well or better than dopamine. It was the first dopamine D1 receptor agonist that had potent antiparkinsonian activity in a primate model of Parkinson's disease. Dihydrexidine produces hypothermia. Dihydrexidine has been shown to alleviate cognitive deficits or enhance cognitive performance in a number of animal models of cognition. It is under investigation for the improving the cognitive and working memory deficits in schizophrenia and schizotypal disorder.
CNS Activity
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/17596915
20 mg over 15 min
Route of Administration:
Other
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123039-93-0
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32D64VH037
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DTXSID00894188
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5311070
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DB12890
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C061532
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admin on Sat Dec 16 05:49:17 GMT 2023 , Edited by admin on Sat Dec 16 05:49:17 GMT 2023
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DIHYDREXIDINE
Created by
admin on Sat Dec 16 05:49:17 GMT 2023 , Edited by admin on Sat Dec 16 05:49:17 GMT 2023
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SUBSTANCE RECORD