Details
Stereochemistry | EPIMERIC |
Molecular Formula | C21H30N4O4.C4H6O6 |
Molecular Weight | 552.5741 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 3 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCOC1=C(C=C(C(N)=C1)[N+]([O-])=O)C(=O)NC2CCN(CC3CCC=CC3)CC2
InChI
InChIKey=HVANMRCHFMTSEG-LREBCSMRSA-N
InChI=1S/C21H30N4O4.C4H6O6/c1-2-29-20-13-18(22)19(25(27)28)12-17(20)21(26)23-16-8-10-24(11-9-16)14-15-6-4-3-5-7-15;5-1(3(7)8)2(6)4(9)10/h3-4,12-13,15-16H,2,5-11,14,22H2,1H3,(H,23,26);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
Cinitapride is an agonist of 5-HT4 and 5-HT1 receptors and antagonist of 5-HT2 receptors. Cinitapride is marketed worldwide for the treatment of gastrointestinal disorders related to motility such as indigestion or functional or non-ulcer dyspepsia, gastroesophageal reflux diseases, delay in gastric emptying and vomiting.
Approval Year
PubMed
Title | Date | PubMed |
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[Metoclopramide versus cinitapride in the treatment of functional dyspepsia]. | 1993 Jul |
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Cinitapride protects against ethanol-induced gastric mucosal injury in rats: role of 5-hydroxytryptamine, prostaglandins and sulfhydryl compounds. | 1997 Apr |
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Effects of cinitapride on gastric ulceration and secretion in rats. | 1998 Mar |
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100000090189
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SUB01312MIG
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1207859-16-2
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2Z90GEN540
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m3565
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DBSALT002860
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6917844
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96623-56-2
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NON-SPECIFIC STOICHIOMETRY |
SUBSTANCE RECORD