Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H20F3N3O4.ClH |
| Molecular Weight | 447.836 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.C[C@H]1CN(CCN1)C2=C(OC(F)F)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O
InChI
InChIKey=AWPMTCKEQGUMTG-FVGYRXGTSA-N
InChI=1S/C19H20F3N3O4.ClH/c1-9-7-24(5-4-23-9)15-13(20)6-11-14(17(15)29-19(21)22)25(10-2-3-10)8-12(16(11)26)18(27)28;/h6,8-10,19,23H,2-5,7H2,1H3,(H,27,28);1H/t9-;/m0./s1
DescriptionCurator's Comment: Description was created based on several sources, including http://www.ncbi.nlm.nih.gov/pubmed/8723467
Curator's Comment: Description was created based on several sources, including http://www.ncbi.nlm.nih.gov/pubmed/8723467
Cadrofloxacin hydrochloride was studied for the treatment of bacterial infections. The compound was originally developed by UBE and Daiichi Sankyo. However, this study was discontinued. The compound currently was developed by Hengrui. Cadrofloxacin showed potent bactericidal activity against S. aureus, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
Originator
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Antimicrobial activity of CS-940, a new trifluorinated quinolone. | 1995 Oct |
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| [Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media]. | 1996 Aug |
|
| [In vitro anti-MAC activities of new quinolones in focus (1)]. | 1996 Sep |
Patents
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128427-55-4
Created by
admin on Sat Dec 16 05:49:31 GMT 2023 , Edited by admin on Sat Dec 16 05:49:31 GMT 2023
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9889840
Created by
admin on Sat Dec 16 05:49:31 GMT 2023 , Edited by admin on Sat Dec 16 05:49:31 GMT 2023
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2XR10ID7XQ
Created by
admin on Sat Dec 16 05:49:31 GMT 2023 , Edited by admin on Sat Dec 16 05:49:31 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
