U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C16H25NO2
Molecular Weight 263.3752
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUTETAMATE

SMILES

CCC(C(=O)OCCN(CC)CC)C1=CC=CC=C1

InChI

InChIKey=CKWHSYRZDLWQFV-UHFFFAOYSA-N
InChI=1S/C16H25NO2/c1-4-15(14-10-8-7-9-11-14)16(18)19-13-12-17(5-2)6-3/h7-11,15H,4-6,12-13H2,1-3H3

HIDE SMILES / InChI
Butetamate is a cough suppressant. It exerts antispasmodic, bronchodilator and anticholinergic properties.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
HELIPHENICOL

Approved Use

Acute cough due to variety of causes, especially dry cough, suppression of preoperative and postoperative cough in surgery and bronchoscopy. whooping cough.

Sample Use Guides

Solution containing 3 mg/ml butetamate citrate. Children: 1 ml/kg/day. Adults: 10 ml every 6 hours.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
BUTETAMATE
INN   WHO-DD  
INN  
Official Name English
butetamate [INN]
Common Name English
HH-105
Code English
2-(DIETHYLAMINO)ETHYL 2-PHENYLBUTYRATE
Systematic Name English
(±)-2-(DIETHYLAMINO)ETHYL 2-PHENYLBUTYRATE
Systematic Name English
HH105
Code English
BUTETHAMATE CITRATE
Common Name English
Butetamate [WHO-DD]
Common Name English
BUTETHAMATE [MI]
Common Name English
BUTETHAMATE
MI  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29698
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
Code System Code Type Description
ECHA (EC/EINECS)
237-817-9
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
RXCUI
156762
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
ALTERNATIVE
PUBCHEM
27368
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
RXCUI
235942
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
NCI_THESAURUS
C73176
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
RXCUI
392938
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
ALTERNATIVE
FDA UNII
2VO6TC90PU
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
ChEMBL
CHEMBL1623049
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
DRUG CENTRAL
445
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
INN
2296
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
SMS_ID
100000088609
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
MESH
C006843
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
CAS
14007-64-8
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
EVMPD
SUB06014MIG
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY
MERCK INDEX
m2795
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID8045640
Created by admin on Sat Dec 16 15:49:44 GMT 2023 , Edited by admin on Sat Dec 16 15:49:44 GMT 2023
PRIMARY