BUTETAMATE CITRATE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H25NO2.C6H8O7
Molecular Weight	455.4987
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCC(C(=O)OCCN(CC)CC)C1=CC=CC=C1

InChI

InChIKey=VVNURWKSPYZZCI-UHFFFAOYSA-N

InChI=1S/C16H25NO2.C6H8O7/c1-4-15(14-10-8-7-9-11-14)16(18)19-13-12-17(5-2)6-3;7-3(8)1-6(13,5(11)12)2-4(9)10/h7-11,15H,4-6,12-13H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

HIDE SMILES / InChI

Molecular Formula	C16H25NO2
Molecular Weight	263.3752
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	C6H8O7
Molecular Weight	192.1235
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://pharmaffiliates.com/butetamate-citrate/797/butetamate-citrate-api-impurity | http://www.laboratorio-ariston.com.ar/productos/wp-content/uploads/Heliphenicol-1.pdf

Butetamate is a cough suppressant. It exerts antispasmodic, bronchodilator and anticholinergic properties.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
acetylcholine receptor activity 5 Target ID: GO:0015464 Sources: http://www.laboratorio-ariston.com.ar/productos/wp-content/uploads/Heliphenicol-1.pdf	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Cough 106 Sources: http://www.laboratorio-ariston.com.ar/productos/wp-content/uploads/Heliphenicol-1.pdf	Primary		Approved 8583	HELIPHENICOL Approved Use Acute cough due to variety of causes, especially dry cough, suppression of preoperative and postoperative cough in surgery and bronchoscopy. whooping cough.

Sample Use Guides

In Vivo Use Guide

Solution containing 3 mg/ml butetamate citrate. Children: 1 ml/kg/day. Adults: 10 ml every 6 hours.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:53:15 GMT 2025` Edited by `admin` on `Mon Mar 31 18:53:15 GMT 2025`
Record UNII	70430R0X79
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTETAMATE CITRATE

Common Name

English

BENZENEACETIC ACID, .ALPHA.-ETHYL-, 2-(DIETHYLAMINO)ETHYL ESTER, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)

Preferred Name

English

BUTETHAMATE CITRATE [MI]

Common Name

English

BUTETAMATE CITRATE [MART.]

Common Name

English

NSC-11781

Code

English

Butetamate citrate [WHO-DD]

Common Name

English

Code System Code Type Description

SMS_ID

100000084859