Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.6529 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 9 / 9 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC(=O)[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChIKey=JQMQKOQOLPGBBE-ZNCJEFCDSA-N
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-25(29)24-15-19(28)11-13-27(24,5)23(20)12-14-26(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,26-,27-/m1/s1
6-ketocholestanol (5 alpha-Cholestan-3 beta-ol-6-one), a compound increases the membrane dipole potential, it was shown that 6-ketocholestanol was incorporated into unilamellar liposomes and was used as a skin pre-treatment. There was a positive effect of 6-ketocholestanol on the sodium-fluorescein diffusion in all skin types.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Interaction of phloretin and 6-ketocholestanol with DPPC-liposomes as phospholipid model membranes. | 2005-04-27 |
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| Influence of 6-ketocholestanol on skin permeation of 5-aminolevulinic acid and evaluation of chemical stability. | 2004-11 |
|
| 6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes. | 1997-01-16 |
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102008
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2V12D4A742
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178278
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DTXSID10922441
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214-640-5
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C063833
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1175-06-0
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SUBSTANCE RECORD
