Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C27H46O2 |
Molecular Weight | 402.6529 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC(=O)[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI
InChIKey=JQMQKOQOLPGBBE-ZNCJEFCDSA-N
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-25(29)24-15-19(28)11-13-27(24,5)23(20)12-14-26(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,26-,27-/m1/s1
Molecular Formula | C27H46O2 |
Molecular Weight | 402.6529 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/12711454
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12711454
6-ketocholestanol (5 alpha-Cholestan-3 beta-ol-6-one), a compound increases the membrane dipole potential, it was shown that 6-ketocholestanol was incorporated into unilamellar liposomes and was used as a skin pre-treatment. There was a positive effect of 6-ketocholestanol on the sodium-fluorescein diffusion in all skin types.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: lipid membrane Sources: https://www.ncbi.nlm.nih.gov/pubmed/15814239 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9030261
Curator's Comment: In planar bilayer phospholipid membrane (BLMs) 6-ketocholestanol not only fails to reverse the effect of SF6847, but even enhances the conductivity increase caused by this uncoupler.
Unknown
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:03:44 GMT 2023
by
admin
on
Fri Dec 15 16:03:44 GMT 2023
|
Record UNII |
2V12D4A742
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
102008
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
2V12D4A742
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
178278
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
DTXSID10922441
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
214-640-5
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
C063833
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY | |||
|
1175-06-0
Created by
admin on Fri Dec 15 16:03:44 GMT 2023 , Edited by admin on Fri Dec 15 16:03:44 GMT 2023
|
PRIMARY |