Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C26H42NO5.Na |
| Molecular Weight | 471.6051 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 10 / 10 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCC([O-])=O
InChI
InChIKey=AAYACJGHNRIFCT-LWADHXPTSA-M
InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-;/m1./s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| pH-Solubility relations of chenodeoxycholic and ursodeoxycholic acids: physical-chemical basis for dissimilar solution and membrane phenomena. | 1980 Jan |
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| Positions of conjugation of bile acids with glucose and N-acetylglucosamine in vitro. | 1994 Sep |
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| Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. | 2005 Jan |
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| Human multidrug resistance protein 2 transports the therapeutic bile salt tauroursodeoxycholate. | 2007 Feb |
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| p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. | 2007 Nov 23 |
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| Glycoursodeoxycholic acid and interleukin-10 modulate the reactivity of rat cortical astrocytes to unconjugated bilirubin. | 2007 Sep |
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| Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. | 2008 Feb |
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| Determination of bile acids in human serum by on-line restricted access material-ultra high-performance liquid chromatography-mass spectrometry. | 2008 Jun 15 |
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| Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid. | 2008 Mar |
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| Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents. | 2009 |
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| Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans. | 2009 Jun |
|
| Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells. | 2010 Feb |
|
| Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid. | 2010 Jan |
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92411-07-9
Created by
admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
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2SMU62O28G
Created by
admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
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53391168
Created by
admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
