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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H42NO5.Na
Molecular Weight 471.6051
Optical Activity UNSPECIFIED
Defined Stereocenters 10 / 10
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URSODEOXYCHOLYLGLYCINE SODIUM

SMILES

[Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(=O)NCC([O-])=O

InChI

InChIKey=AAYACJGHNRIFCT-LWADHXPTSA-M
InChI=1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-;/m1./s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C26H42NO5
Molecular Weight 448.6154
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 10
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Positions of conjugation of bile acids with glucose and N-acetylglucosamine in vitro.
1994 Sep
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
1998 Jan
Whole-cell response characteristics of ciliated and microvillous olfactory receptor neurons to amino acids, pheromone candidates and urine in rainbow trout.
2001 Nov
Interactions of combined bile acids on hepatocyte viability: cytoprotection or synergism.
2002 Feb 7
High-performance liquid chromatographic mass spectrometric method for the determination of ursodeoxycholic acid and its glycine and taurine conjugates in human plasma.
2003 Dec 25
Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor.
2003 Oct
Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
2005 Jan
Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid.
2008 Mar
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:00:11 GMT 2023
Edited
by admin
on Fri Dec 15 15:00:11 GMT 2023
Record UNII
2SMU62O28G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
URSODEOXYCHOLYLGLYCINE SODIUM
Common Name English
SODIUM GLYCOURSODEOXYCHOLATE
Common Name English
GLYCINE, N-((3.ALPHA.,5.BETA.,7.BETA.)-3,7-DIHYDROXY-24-OXOCHOLAN-24-YL)-, SODIUM SALT (1:1)
Systematic Name English
GLYCOURSODEOXYCHOLIC ACID, SODIUM SALT
Common Name English
SODIUM GLYCOURSODESOXYCHOLATE
Common Name English
GLYCINE, N-((3.ALPHA.,5.BETA.,7.BETA.)-3,7-DIHYDROXY-24-OXOCHOLAN-24-YL)-, MONOSODIUM SALT
Common Name English
Code System Code Type Description
CAS
92411-07-9
Created by admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
PRIMARY
FDA UNII
2SMU62O28G
Created by admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
PRIMARY
PUBCHEM
53391168
Created by admin on Fri Dec 15 15:00:11 GMT 2023 , Edited by admin on Fri Dec 15 15:00:11 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE