Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C24H30N4O.C4H4O4 |
| Molecular Weight | 506.5934 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)\C=C\C(O)=O.CCN(CC)CCCNC(=O)CN1N=CC(=C1C2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=KKMOBFCMCCFTDX-WLHGVMLRSA-N
InChI=1S/C24H30N4O.C4H4O4/c1-3-27(4-2)17-11-16-25-23(29)19-28-24(21-14-9-6-10-15-21)22(18-26-28)20-12-7-5-8-13-20;5-3(6)1-2-4(7)8/h5-10,12-15,18H,3-4,11,16-17,19H2,1-2H3,(H,25,29);1-2H,(H,5,6)(H,7,8)/b;2-1+
Ipazilide is an antiarrhythmic agent that prolongs ventricular refractoriness and possesses antiectopic activity. In clinical trials ipazilide administrations leads to dose- and time-dependent in decrease cardiac index and arterial pressure. Left ventricular filling pressure, right atrial pressure, and heart rate were not altered by ipazilide. Plasma concentrations of ipazilide peaked 90 minutes after administration of 100 or 200 of the drug, but peak concentrations were noted 3 hours after administration of 400 mg. The hemodynamic response correlated with the plasma concentration of ipazilide determined contemporaneously.
Approval Year
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NCI_THESAURUS |
C47793
Created by
admin on Fri Dec 15 15:59:06 GMT 2023 , Edited by admin on Fri Dec 15 15:59:06 GMT 2023
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C076683
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2MI60P494I
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5284403
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CHEMBL2111169
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C81425
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115436-74-3
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AA-112
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DTXSID9020744
Created by
admin on Fri Dec 15 15:59:06 GMT 2023 , Edited by admin on Fri Dec 15 15:59:06 GMT 2023
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PRIMARY |
ACTIVE MOIETY
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD
