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Details

Stereochemistry RACEMIC
Molecular Formula C8H12N2.ClH
Molecular Weight 172.655
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of MEBANAZINE HYDROCHLORIDE

SMILES

Cl.CC(NN)C1=CC=CC=C1

InChI

InChIKey=FLMNJZPWUCHXNJ-UHFFFAOYSA-N
InChI=1S/C8H12N2.ClH/c1-7(10-9)8-5-3-2-4-6-8;/h2-7,10H,9H2,1H3;1H

HIDE SMILES / InChI
Mebanazine is an inhibitor of monoamine oxidase. It was introduced in the 1960s for the treatment of depression and was marketed under trade name Actomol. The drug was withdrawn from the market due to hepatotoxicity. In addition to its antidepressant effect, the drug was found to possess an anorexic action and in animal models, it potentiated the hypoglycemic response to insulin and delayed the recovery of blood glucose levels to normal.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Name Type Language
MEBANAZINE HYDROCHLORIDE
Common Name English
HYDRAZINE, (.ALPHA.-METHYLBENZYL)-, MONOHYDROCHLORIDE
Systematic Name English
HYDRAZINE, (1-PHENYLETHYL)-, HYDROCHLORIDE (1:1)
Systematic Name English
HYDRAZINE, (1-PHENYLETHYL)-, MONOHYDROCHLORIDE
Systematic Name English
Code System Code Type Description
PUBCHEM
34527
Created by admin on Sat Dec 16 09:53:58 GMT 2023 , Edited by admin on Sat Dec 16 09:53:58 GMT 2023
PRIMARY
CAS
29248-55-3
Created by admin on Sat Dec 16 09:53:58 GMT 2023 , Edited by admin on Sat Dec 16 09:53:58 GMT 2023
PRIMARY
FDA UNII
2M3FU59FTM
Created by admin on Sat Dec 16 09:53:58 GMT 2023 , Edited by admin on Sat Dec 16 09:53:58 GMT 2023
PRIMARY
EPA CompTox
DTXSID90951850
Created by admin on Sat Dec 16 09:53:58 GMT 2023 , Edited by admin on Sat Dec 16 09:53:58 GMT 2023
PRIMARY