THIFLUZAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H6Br2F6N2O2S
Molecular Weight	528.062
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC(=C(S1)C(=O)NC2=C(Br)C=C(OC(F)(F)F)C=C2Br)C(F)(F)F

InChI

InChIKey=WOSNCVAPUOFXEH-UHFFFAOYSA-N

InChI=1S/C13H6Br2F6N2O2S/c1-4-22-10(12(16,17)18)9(26-4)11(24)23-8-6(14)2-5(3-7(8)15)25-13(19,20)21/h2-3H,1H3,(H,23,24)

HIDE SMILES / InChI

Description
Sources: https://www.chemservice.com/news/2014/06/get-a-better-picture-of-thifluzamide/ | https://www.ncbi.nlm.nih.gov/pubmed/26453237

Thifluzamide is a powerful and effective fungicide. When used safely and correctly it can be effective on rice and other crops because of improved water dispersal techniques. Thifluzamide is highly active against Basidiomycete fungi, in particular Rhizoctonia solani, primarily in rice, potatoes, and turf markets.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Ceratobasidium cereale 1 Target ID: CHEMBL613340 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26453237 \| https://www.ncbi.nlm.nih.gov/pubmed/27415408	Inhibitor 8504
succinate dehydrogenase activity 3 Target ID: GO:0000104 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26453237 \| https://www.ncbi.nlm.nih.gov/pubmed/27415408	Inhibitor 8504

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Adsorption-desorption, persistence and leaching behavior of thifluzamide in alluvial soil.	2004-11	15350409

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

The EC50 values for thifluzamidein inhibiting mycelial growth of R. cerealis varied from 0.025 to0.36 ug/ml, with a mean of 0.064 ± 0.013 ug/ml.

Name

Type

Language

THIFLUZAMIDE [ISO]

Preferred Name

English

THIFLUZAMIDE

Common Name

English

2',6'-DIBROMO-2-METHYL-4'-TRIFLUOROMETHOXY-4-TRIFLUOROMETHYL-1,3-THIAZOLE-5-CARBOXANILIDE

Systematic Name

English

THIFLUZAMIDE [MI]

Common Name

English

N-(2,6-DIBROMO-4-(TRIFLUOROMETHOXY)PHENYL)-2-METHYL-4-(TRIFLUOROMETHYL)-5-THIAZOLECARBOXAMIDE

Systematic Name

English

Code System Code Type Description

PUBCHEM

86389