Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C12H19NO2.C4H6O4 |
| Molecular Weight | 327.3728 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)CCC(O)=O.CCCCNCC(O)C1=CC=C(O)C=C1
InChI
InChIKey=NDGDFKFGBZCILN-UHFFFAOYSA-N
InChI=1S/C12H19NO2.C4H6O4/c1-2-3-8-13-9-12(15)10-4-6-11(14)7-5-10;5-3(6)1-2-4(7)8/h4-7,12-15H,2-3,8-9H2,1H3;1-2H2,(H,5,6)(H,7,8)
Bamethan (butyl-sympatol or vasculat) is an adrenaline derivative developed by C. H. Boehringer Sohn. Bamethan shows a depressor action on peripheral blood vessels as a result of the peripheral vasodilating action caused by stimulation of adrenergic beta-receptor. Bamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | VASCULAT Approved UseBamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency. |
PubMed
| Title | Date | PubMed |
|---|---|---|
| The effect of bamethan on cardiovascular response. | 1966 Jan-Feb |
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| Development and validation of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of ribavirin in human plasma and serum. | 2002 Jun 20 |
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| Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids. | 2005 |
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2GLO6IOP6Y
Created by
admin on Sat Dec 16 08:31:58 GMT 2023 , Edited by admin on Sat Dec 16 08:31:58 GMT 2023
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133065418
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235933
Created by
admin on Sat Dec 16 08:31:58 GMT 2023 , Edited by admin on Sat Dec 16 08:31:58 GMT 2023
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59547-50-1
Created by
admin on Sat Dec 16 08:31:58 GMT 2023 , Edited by admin on Sat Dec 16 08:31:58 GMT 2023
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ACTIVE MOIETY
SUBSTANCE RECORD
