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Details

Stereochemistry RACEMIC
Molecular Formula C12H19NO2.C4H6O4
Molecular Weight 327.3728
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BAMETHAN SUCCINATE

SMILES

OC(=O)CCC(O)=O.CCCCNCC(O)C1=CC=C(O)C=C1

InChI

InChIKey=NDGDFKFGBZCILN-UHFFFAOYSA-N
InChI=1S/C12H19NO2.C4H6O4/c1-2-3-8-13-9-12(15)10-4-6-11(14)7-5-10;5-3(6)1-2-4(7)8/h4-7,12-15H,2-3,8-9H2,1H3;1-2H2,(H,5,6)(H,7,8)

HIDE SMILES / InChI

Molecular Formula C12H19NO2
Molecular Weight 209.2848
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula C4H6O4
Molecular Weight 118.088
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Bamethan (butyl-sympatol or vasculat) is an adrenaline derivative developed by C. H. Boehringer Sohn. Bamethan shows a depressor action on peripheral blood vessels as a result of the peripheral vasodilating action caused by stimulation of adrenergic beta-receptor. Bamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
VASCULAT

Approved Use

Bamethan has been used abroad in the treatment of certain peripheral vascular and circulatory disturbances, such as vasospastic conditions, arteriosclerotic peripheral vascular disease, Raynaud's syndrome, occlusive vascular disease of the legs, the post-thrombotic syndrome, degenerative muscular disorders, and other conditions involving peripheral vascular insuffciency.
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

75-100 mg
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:31:57 UTC 2023
Edited
by admin
on Sat Dec 16 08:31:57 UTC 2023
Record UNII
2GLO6IOP6Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BAMETHAN SUCCINATE
WHO-DD  
Common Name English
Bamethan succinate [WHO-DD]
Common Name English
LARGOPHERIN
Brand Name English
PROVASCUL
Brand Name English
BENZENEMETHANOL, .ALPHA.-((BUTYLAMINO)METHYL)-4-HYDROXY-, BUTANEDIOATE (SALT)
Common Name English
Code System Code Type Description
FDA UNII
2GLO6IOP6Y
Created by admin on Sat Dec 16 08:31:58 UTC 2023 , Edited by admin on Sat Dec 16 08:31:58 UTC 2023
PRIMARY
PUBCHEM
133065418
Created by admin on Sat Dec 16 08:31:58 UTC 2023 , Edited by admin on Sat Dec 16 08:31:58 UTC 2023
PRIMARY
RXCUI
235933
Created by admin on Sat Dec 16 08:31:58 UTC 2023 , Edited by admin on Sat Dec 16 08:31:58 UTC 2023
PRIMARY RxNorm
CAS
59547-50-1
Created by admin on Sat Dec 16 08:31:58 UTC 2023 , Edited by admin on Sat Dec 16 08:31:58 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY