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Details

Stereochemistry RACEMIC
Molecular Formula C4H4O5.2Na
Molecular Weight 178.0511
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM MALATE

SMILES

[Na+].[Na+].OC(CC([O-])=O)C([O-])=O

InChI

InChIKey=WPUMTJGUQUYPIV-UHFFFAOYSA-L
InChI=1S/C4H6O5.2Na/c5-2(4(8)9)1-3(6)7;;/h2,5H,1H2,(H,6,7)(H,8,9);;/q;2*+1/p-2

HIDE SMILES / InChI

Description

Malic acid is a tart-tasting organic dicarboxylic acid that contributes to the taste of many sour or tart foods such as apples. Sodium Malate is the sodium salt of Malic Acid. Malic Acid and Sodium Malate can be found in a wide range of cosmetics and personal care products. Sodium Malate functions as a skin conditioning agent-humectant. As a food additive, Sodium Malate has the E number E350. Sodium Malate has demonstrated protective effect on cisplatin-induced toxicity in mice. Sodium malate could become a useful agent for the reduction of CDDP-induced toxicity, particularly nephrotoxicity and hepatotoxicity.

Originator

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct
Secondary
Unknown
Preventing
Unknown
Curative
ACERBINE

PubMed

Sample Use Guides

In Vivo Use Guide
Apply Acerbine solution (malic acid, salicylic acid, benzoic acid) to the wound or damaged skin two or more times daily or moisten the dressing again. Once scar formation begins, one application a day is generally sufficient.
Route of Administration: Topical
In Vitro Use Guide
Unknown