5-HYDROXYTHALIDOMIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H10N2O5
Molecular Weight	274.2289
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1

InChI

InChIKey=LJBQRRQTZUJWRC-UHFFFAOYSA-N

InChI=1S/C13H10N2O5/c16-6-1-2-7-8(5-6)13(20)15(12(7)19)9-3-4-10(17)14-11(9)18/h1-2,5,9,16H,3-4H2,(H,14,17,18)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate.	2010 Jun 21	20443640
Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide.	2014 Jan 21	24350712

Patents

Name

Type

Language

5-HYDROXYTHALIDOMIDE

Common Name

English

PHTHALIMIDE, N-(2,6-DIOXO-3-PIPERIDYL)-4-HYDROXY-

Systematic Name

English

5-HYDROXY THALIDOMIDE, (±)-

Common Name

English

1H-ISOINDOLE-1,3(2H)-DIONE, 2-(2,6-DIOXO-3-PIPERIDINYL)-5-HYDROXY-

Systematic Name

English

5-HYDROXY THALIDOMIDE

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID40983186

Created by admin on Sat Dec 16 09:10:35 GMT 2023 , Edited by admin on Sat Dec 16 09:10:35 GMT 2023

PRIMARY

PUBCHEM

5743568

Created by admin on Sat Dec 16 09:10:35 GMT 2023 , Edited by admin on Sat Dec 16 09:10:35 GMT 2023

PRIMARY

CAS

64567-60-8

Created by admin on Sat Dec 16 09:10:35 GMT 2023 , Edited by admin on Sat Dec 16 09:10:35 GMT 2023

PRIMARY

FDA UNII

29V976C3CJ

Created by admin on Sat Dec 16 09:10:35 GMT 2023 , Edited by admin on Sat Dec 16 09:10:35 GMT 2023

PRIMARY

PARENT (METABOLITE)


					4Z8R6ORS6L

THALIDOMIDE

SUBSTANCE RECORD


					29V976C3CJ

5-HYDROXYTHALIDOMIDE