AMOPROXAN

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H35NO7
Molecular Weight	425.5158
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)OC(COCCC(C)C)CN2CCOCC2

InChI

InChIKey=YOKPRDAUBGOISU-UHFFFAOYSA-N

InChI=1S/C22H35NO7/c1-16(2)6-9-29-15-18(14-23-7-10-28-11-8-23)30-22(24)17-12-19(25-3)21(27-5)20(13-17)26-4/h12-13,16,18H,6-11,14-15H2,1-5H3

HIDE SMILES / InChI

Description
Sources: https://books.google.ru/books?id=_J2ti4EkYpkC&pg=PA292&dq=AMOPROXAN retrieved from Pharmaceutical Manufacturing Encyclopedia William Andrew Publishing, p.292
Curator's Comment: https://books.google.ru/books?id=mDLYCQAAQBAJ&pg=PA135&lpg=PA135&dq=AMOPROXAN retrieved from Toxicology of the Eye: Effects on the Eyes and Visual System from Chemicals, Drugs, Metals and Minerals, Plants, Toxins, and Venoms; Also, Systemic Side Effects from Eye med (2-Volume Set), p.135

Amoproxan (Mederel, Mexderel), a coronary artery dilator and anti-arrhythmic, apparently withdrawn from production, produced pellagroid skin changes and several cases of axial optic neuropathy in France.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Angina pectoris 106 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5437771	Primary		Withdrawn	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

AMOPROXAN

Official Name

English

.ALPHA.-(ISOPENTYLOXYMETHYL)-4-MORPHOLINEETHANOL 3,4,5-TRIMETHOXYBENZOATE (ESTER)

Common Name

English

amoproxan [INN]

Common Name

English

CERM 730

Code

English

AMOPROXAN [MI]

Common Name

English

CERM-730

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C29707