Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H5Hg.C2H3O2.H3N |
| Molecular Weight | 353.77 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
N.CC([O-])=O.[Hg+]C1=CC=CC=C1
InChI
InChIKey=LPDJEBDOSVRHKE-UHFFFAOYSA-M
InChI=1S/C6H5.C2H4O2.Hg.H3N/c1-2-4-6-5-3-1;1-2(3)4;;/h1-5H;1H3,(H,3,4);;1H3/q;;+1;/p-1
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/22514262 | https://www.ncbi.nlm.nih.gov/pubmed/6277015 | https://www.ncbi.nlm.nih.gov/pubmed/21260329DOI: 10.1007/BF02861085 | DOI: 10.1080/09670877409413645 | Environmental Administrative Decisions: Decisions of the United States Environmental Protection Agency. 1972-1985, page 223, retrieved from: https://books.google.ru/books?id=QiB5OUaJIv4C
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22514262 | https://www.ncbi.nlm.nih.gov/pubmed/6277015 | https://www.ncbi.nlm.nih.gov/pubmed/21260329DOI: 10.1007/BF02861085 | DOI: 10.1080/09670877409413645 | Environmental Administrative Decisions: Decisions of the United States Environmental Protection Agency. 1972-1985, page 223, retrieved from: https://books.google.ru/books?id=QiB5OUaJIv4C
Phenylmercuric ammonium acetate is a fungicide and bactericide. It is used for the seed treatment.
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL612756 |
|||
Target ID: CHEMBL612633 |
|||
Target ID: GO:0070527 |
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Target ID: CHEMBL614430 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Curative | Unknown Approved UseUnknown |
|||
| Curative | Unknown Approved UseUnknown |
|||
| Preventing | Volpar gel Approved UseSpermicide Launch Date1936 |
Doses
| Dose | Population | Adverse events |
|---|---|---|
0.01 % 1 times / day multiple, topical Dose: 0.01 %, 1 times / day Route: topical Route: multiple Dose: 0.01 %, 1 times / day Sources: |
healthy, 54 years |
Disc. AE: Contact urticaria... AEs leading to discontinuation/dose reduction: Contact urticaria Sources: |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Contact urticaria | Disc. AE | 0.01 % 1 times / day multiple, topical Dose: 0.01 %, 1 times / day Route: topical Route: multiple Dose: 0.01 %, 1 times / day Sources: |
healthy, 54 years |
Overview
| CYP3A4 | CYP2C9 | CYP2D6 | hERG |
|---|---|---|---|
OverviewOther
| Other Inhibitor | Other Substrate | Other Inducer |
|---|---|---|
Drug as perpetrator
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| yes [Activation 1 uM] | ||||
| yes [Activation 1.8 uM] | ||||
| yes [Activation 22 uM] | ||||
| yes [Activation 3.2 uM] | ||||
| yes [Activation 4.5 uM] | ||||
| yes [Activation 8.9 uM] |
PubMed
| Title | Date | PubMed |
|---|---|---|
| A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. | 2015-09 |
|
| Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. | 2015-05 |
|
| The antifungal properties of chlorhexidine digluconate and cetylpyrinidinium chloride on oral Candida. | 2012-07 |
|
| The role of mycelium production and a MAPK-mediated immune response in the C. elegans-Fusarium model system. | 2012-07 |
|
| Mercury (Hg) and lead (Pb) in interior and exterior New Orleans house paint films. | 2008-06 |
|
| Characterization and inhibition of SARS-coronavirus main protease. | 2006 |
|
| [Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations]. | 2004-05 |
|
| [Contact eczema caused by pesticides in East Germany]. | 1989 |
|
| Bacterial organomercurial lyase: overproduction, isolation, and characterization. | 1986-11-04 |
Patents
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
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|---|---|---|---|---|---|
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SUBSTANCE RECORD
