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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H20O2
Molecular Weight 196.286
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BORNYL ACETATE, (-)-

SMILES

CC(=O)O[C@@H]1C[C@@H]2CC[C@@]1(C)C2(C)C

InChI

InChIKey=KGEKLUUHTZCSIP-HOSYDEDBSA-N
InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10+,12+/m0/s1

HIDE SMILES / InChI

Description

Bornyl acetate is the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, which has displayed an anti-inflammatory effect. In addition was shown, that this compound had therapeutic potentials for the osteoarthritis and may be developed as a preventive agent for lung inflammatory diseases. In combination with 5-fluorouracil, bornyl acetate possesses the anticancer activity by inducing apoptosis, DNA fragmentation as well as G2/M cell cycle arrest.

Approval Year

2014
503
Targets

Targets

Primary TargetPharmacologyConditionPotency
Blocker
555
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Preventing
Preclinical
Unknown

Approved Use

Unknown
Primary
Basic research
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
[Study on the chemical constituents of the volatile oil from Lysimachia trientaloides Hemsl].
2002 May
An unusual and persistent contamination of drinking water by cutting oil.
2003 Feb
Quality assessment of Flos Chrysanthemi Indici from different growing areas in China by solid-phase microextraction-gas chromatography-mass spectrometry.
2004 Aug 27
[Studies on the analgesic and anti-inflammatory effect of bornyl acetate in volatile oil from Amomum villosum].
2004 Jun
The effect of selected monoterpenoids on the cellular slime mold, Dictyostelium discoideum NC4.
2004 Jun
Ion exchange resins as catalyst for the isomerization of alpha-pinene to camphene.
2004 Jun
Essential oil of Valeriana officinalis L. cultivars and their antimicrobial activity as influenced by harvesting time under commercial organic cultivation.
2004 Jun 16
Anticonvulsant activity and chemical composition of Artemisia dracunculus L. essential oil.
2004 Oct
Chemical composition and antimicrobial activity of the essential oils of Chrysanthemum indicum.
2005 Jan 4
25 years of natural product R&D with New South Wales agriculture.
2005 Oct 31
Ethnoveterinary medicines used for ruminants in British Columbia, Canada.
2007 Feb 26
Terpenoid compositions, and antioxidant and antimicrobial properties of the rhizome essential oils of different Hedychium species.
2008 Feb
GC/MS of terpenes in walnut-tree leaves after accelerated solvent extraction.
2008 Jan
[Characterization of chemical components of essential oil from flowers of Chrysanthemum morifolium produced in Anhui province].
2008 Oct
Antinociceptive effect and GC/MS analysis of Rosmarinus officinalis L. essential oil from its aerial parts.
2009 Apr
Acaricidal activities of major constituents of essential oil of Juniperus chinensis leaves against house dust and stored food mites.
2009 Aug
Essential oil variability in natural populations of Picea omorika, a rare European conifer.
2009 Feb
Composition and seasonal variation of the essential oil from Abies sachalinensis from Hokkaido, Japan.
2009 Jun
Radical Scavenging Activity of the Essential Oil of Silver Fir (Abies alba).
2009 May
Supercritical fluid extraction of the volatile oil from Santolina chamaecyparissus.
2009 Sep
Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype.
2010
Compositional variability in essential oil from different parts of Alpinia speciosa from India.
2010 Feb
Salvadora persica.
2010 Jul
Effects of foliar fertilization and arbuscular mycorrhizal colonization on Salvia officinalis L. growth, antioxidant capacity, and essential oil composition.
2010 Mar 15
Relation between developmental stage, sensory properties, and volatile content of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi).
2010 May
Patents

Patents

JP2001064163A
2
JP2004124079A
2
JPH04183797A
4
JPH06313195A
2
JPH08100147A
3
JPH09313582A
2

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
It was shown, that bornyl acetate elevated the expression of IL-11 at both the mRNA and protein levels. Normal human chondrocytes were pretreated with or without bornyl acetate at the concentrations of 50 and 100 ug/mL for 24H, followed by incubated with IL-1b 10 ug/mL for another 24 H.
Name Type Language
BORNYL ACETATE, (-)-
Systematic Name English
L-BORNYL ACETATE
FHFI  
Preferred Name English
(-)-BORNEOL ACETATE
Systematic Name English
L-BORNYL ACETATE [FHFI]
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, ACETATE, (1S-ENDO)-
Common Name English
BORNYL ACETATE, L-
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, 2-ACETATE, (1S,2R,4S)-
Common Name English
1S-ENDO-BORNYL ACETATE
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, ACETATE, (1S,2R,4S)-
Systematic Name English
BORNYL ACETATE L-FORM [MI]
Common Name English
BORNEOL, L-, ACETATE
Common Name English
FEMA NO. 4080
Code English
BORNYL ACETATE L-FORM
MI  
Common Name English
BORNEOL ACETATE, (-)-
Systematic Name English
(-)BRONYL ACETATE
Common Name English
(-)-BORNYL ACETATE (CONSTITUENT OF MYRRH) [DSC]
Common Name English
BORNEOL, ACETATE, (1S,2R,4S)-(-)-
Systematic Name English
LEVO-BORNYL ACETATE
Common Name English
(1S)-1,7,7-TRIMETHYLBICYCLO(2.2.1)-2-HEPTANOL ACETATE
Common Name English
(-)-BORNYL ACETATE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID3052228
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
RXCUI
2395802
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
DAILYMED
24QAP1VCUX
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
MERCK INDEX
m2611
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY Merck Index
SMS_ID
300000035078
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
FDA UNII
24QAP1VCUX
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
JECFA MONOGRAPH
1842
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
PUBCHEM
93009
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
227-101-4
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
CAS
5655-61-8
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
SUBSTANCE RECORD
Structure of BORNYL ACETATE, (-)-
NIH
NCATS
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