Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C12H20O2 |
| Molecular Weight | 196.286 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC[C@](C)([C@@H](C1)OC(C)=O)C2(C)C
InChI
InChIKey=KGEKLUUHTZCSIP-HOSYDEDBSA-N
InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10+,12+/m0/s1
| Molecular Formula | C12H20O2 |
| Molecular Weight | 196.286 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Bornyl acetate is the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, which has displayed an anti-inflammatory effect. In addition was shown, that this compound had therapeutic potentials for the osteoarthritis and may be developed as a preventive agent for lung inflammatory diseases. In combination with 5-fluorouracil, bornyl acetate possesses the anticancer activity by inducing apoptosis, DNA fragmentation as well as G2/M cell cycle arrest.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| 25 years of natural product R&D with New South Wales agriculture. | 2005 Oct 31 |
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| Chemical composition and antimicrobial activity of the essential oil from Ambrosia trifida L. | 2006 Jul 25 |
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| Chemical composition and antibacterial activities of the essential oil from Abies koreana. | 2007 Dec |
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| Simultaneous distillation-extraction of high-value volatile compounds from Cistus ladanifer L. | 2007 Feb 19 |
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| Ethnoveterinary medicines used for ruminants in British Columbia, Canada. | 2007 Feb 26 |
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| Chemical composition and antimicrobial and antioxidant activities of the essential oil and methanol extract of Hippomarathrum microcarpum (Bieb.) from Turkey. | 2007 Feb 7 |
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| Screening of antibacterial activities of twenty-one oxygenated monoterpenes. | 2007 Jul-Aug |
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| Composition and enantiomeric analysis of the essential oil of the fruits and the leaves of Pistacia vera from Greece. | 2007 Jun 30 |
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| Analysis by gas chromatography-mass spectrometry of essential oil from seeds and aerial parts of Ferulago angulata (Schlecht.) Boiss gathered in Nevakoh and Shahoo, Zagross mountain, West of Iran. | 2007 Mar 1 |
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| Essential oil composition and antioxidant activity of aerial parts of Grindelia robusta from Central Italy. | 2007 Sep |
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| Terpenoid compositions, and antioxidant and antimicrobial properties of the rhizome essential oils of different Hedychium species. | 2008 Feb |
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| Essential oil composition of Valeriana officinalis L. roots cultivated in Iran. Comparative analysis between supercritical CO2 extraction and hydrodistillation. | 2008 Feb 8 |
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| Variability of the needle essential oils of Pinus peuce from different populations in Montenegro and Serbia. | 2008 Jul |
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| Context effects on odor processing: an event-related potential study. | 2008 Jul 15 |
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| The clinical pharmacology of intranasal l-methamphetamine. | 2008 Jul 21 |
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| Activity of essential oils and individual components against acetyl- and butyrylcholinesterase. | 2008 Jul-Aug |
|
| Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. | 2008 Jun |
|
| Chemical composition and antimicrobial activity of essential oil from cones of Pinus koraiensis. | 2008 Mar |
|
| Separation and identification of volatile constituents in Artemisia argyi flowers by GC-MS with SPME and steam distillation. | 2008 May-Jun |
|
| [Characterization of chemical components of essential oil from flowers of Chrysanthemum morifolium produced in Anhui province]. | 2008 Oct |
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| Synthesis, chiroptical properties, and their theoretical simulation of some highly rotating benzotricamphor derivatives. | 2009 |
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| Antinociceptive effect and GC/MS analysis of Rosmarinus officinalis L. essential oil from its aerial parts. | 2009 Apr |
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| Acaricidal activities of major constituents of essential oil of Juniperus chinensis leaves against house dust and stored food mites. | 2009 Aug |
|
| Rosmarinus officinalis L.: chemical modifications of the essential oil and evaluation of antioxidant and antimicrobial activity. | 2009 Dec |
|
| Chemical composition of hydrodistilled essential oil of Artemisia incana (L.) Druce and antimicrobial activity against foodborne microorganisms. | 2009 Dec |
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| Essential oil variability in natural populations of Picea omorika, a rare European conifer. | 2009 Feb |
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| Assessment of the allelopathic potential of Juniperus ashei on germination and growth of Bouteloua curtipendula. | 2009 Jan |
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| Identification and quantification of the volatile constituents in Cnidium monnieri using supercritical fluid extraction followed by GC-MS. | 2009 Jan |
|
| Composition and seasonal variation of the essential oil from Abies sachalinensis from Hokkaido, Japan. | 2009 Jun |
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| Radical Scavenging Activity of the Essential Oil of Silver Fir (Abies alba). | 2009 May |
|
| Supercritical fluid extraction of the volatile oil from Santolina chamaecyparissus. | 2009 Sep |
|
| Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype. | 2010 |
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| Analysis of essential oils from different organs of Scutellaria baicalensis. | 2010 Aug |
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| In vitro synergistic efficacy of combination of amphotericin B with Myrtus communis essential oil against clinical isolates of Candida albicans. | 2010 Aug |
|
| Essential oil composition of four endemic Ferulago species growing in Turkey. | 2010 Dec |
|
| Compositional variability in essential oil from different parts of Alpinia speciosa from India. | 2010 Feb |
|
| The chemical composition and antimicrobial activity of the leaf oil of Cupressus lusitanica from Monteverde, Costa Rica. | 2010 Jan |
|
| Misidentification of tansy, Tanacetum macrophyllum, as yarrow, Achillea grandifolia: a health risk or benefit? | 2010 Jan |
|
| Salvadora persica. | 2010 Jul |
|
| [Analysis of the chemical constituents of volatile oil from Asarum insigne by GC-MS]. | 2010 Jul |
|
| A DFT analysis of thermal decomposition reactions important to natural products. | 2010 Jul |
|
| Investigation of the volatile fraction of rosemary infusion extracts. | 2010 Jul-Sep |
|
| The volatile constituents of Salvia leucantha. | 2010 Jun |
|
| Effects of foliar fertilization and arbuscular mycorrhizal colonization on Salvia officinalis L. growth, antioxidant capacity, and essential oil composition. | 2010 Mar 15 |
|
| Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum. | 2010 May |
|
| Relation between developmental stage, sensory properties, and volatile content of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi). | 2010 May |
|
| Essential oil composition and antioxidant and antimicrobial properties of the aerial parts of Salvia eremophila Boiss. from Iran. | 2010 May |
|
| Genetics, phosphorus availability, and herbivore-derived induction as sources of phenotypic variation of leaf volatile terpenes in a pine species. | 2010 Oct |
|
| Volatile oil profiles of the aerial parts of Jordanian garland, Chrysanthemum coronarium. | 2010 Oct |
|
| Essential oils, phenolics, and antioxidant activities of different parts of cumin (Cuminum cyminum L.). | 2010 Oct 13 |
Sample Use Guides
It was shown, that bornyl acetate elevated the expression of IL-11 at both the mRNA and protein levels. Normal human chondrocytes were pretreated with or without bornyl acetate at the concentrations of 50 and 100 ug/mL for 24H, followed by incubated with IL-1b 10 ug/mL for another 24 H.
| Substance Class |
Chemical
Created
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on
Edited
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| Record UNII |
24QAP1VCUX
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| Record Status |
Validated (UNII)
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