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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H20O2
Molecular Weight 196.286
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BORNYL ACETATE, (-)-

SMILES

CC(=O)O[C@@H]1C[C@@H]2CC[C@@]1(C)C2(C)C

InChI

InChIKey=KGEKLUUHTZCSIP-HOSYDEDBSA-N
InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10,4)11(9,2)3/h9-10H,5-7H2,1-4H3/t9-,10+,12+/m0/s1

HIDE SMILES / InChI

Molecular Formula C12H20O2
Molecular Weight 196.286
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Bornyl acetate is the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, which has displayed an anti-inflammatory effect. In addition was shown, that this compound had therapeutic potentials for the osteoarthritis and may be developed as a preventive agent for lung inflammatory diseases. In combination with 5-fluorouracil, bornyl acetate possesses the anticancer activity by inducing apoptosis, DNA fragmentation as well as G2/M cell cycle arrest.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Preventing
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Foliar and cortex oleoresin variability of silver fir (Abies alba Mill.) in Albania.
2001 Jul-Aug
[Study on the chemical constituents of the volatile oil from Lysimachia trientaloides Hemsl].
2002 May
Analysis of the essential oils of the leaves, stems, rhizomes and roots of the medicinal plant Alpinia galanga from southern India.
2003 Jun
Total synthesis of dumsin. 1. Retrosynthetic strategy and the elaboration of key intermediates from (--)-bornyl acetate.
2003 Sep 5
Essential oil of Valeriana officinalis L. cultivars and their antimicrobial activity as influenced by harvesting time under commercial organic cultivation.
2004 Jun 16
[Profile-effect on quality control of Houttuynia cordata injection].
2005 Dec
[Research on the analgesic effect and mechanism of bornyl acetate in volatile oil from amomum villosum].
2005 Jun
Composition, enantiomeric distribution, and antibacterial activity of the essential oil of Achillea ligustica All. from Corsica.
2006 Aug 23
Chemical composition and biological activities of essential oil from the leaves of Sesuvium portulacastrum.
2006 Jan 3
Variation in chemical composition and antibacterial activities of essential oils from two species of Houttuynia THUNB.
2006 Jul
Chemical composition and antimicrobial activity of the essential oil from Ambrosia trifida L.
2006 Jul 25
[Analysis of volatile constituents in leaves of three cypress species by gas chromatography/mass spectrometry].
2006 Mar
Phytochemical analysis of the essential oil of Achillea millefolium L. from various European Countries.
2006 Oct
Chemical composition and antibacterial activities of the essential oil from Abies koreana.
2007 Dec
Simultaneous distillation-extraction of high-value volatile compounds from Cistus ladanifer L.
2007 Feb 19
Ethnoveterinary medicines used for ruminants in British Columbia, Canada.
2007 Feb 26
Screening of antibacterial activities of twenty-one oxygenated monoterpenes.
2007 Jul-Aug
Composition and enantiomeric analysis of the essential oil of the fruits and the leaves of Pistacia vera from Greece.
2007 Jun 30
Essential oil composition and antioxidant activity of aerial parts of Grindelia robusta from Central Italy.
2007 Sep
Essential oil composition of Valeriana officinalis L. roots cultivated in Iran. Comparative analysis between supercritical CO2 extraction and hydrodistillation.
2008 Feb 8
GC/MS of terpenes in walnut-tree leaves after accelerated solvent extraction.
2008 Jan
Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs.
2008 Jun
Synthesis, chiroptical properties, and their theoretical simulation of some highly rotating benzotricamphor derivatives.
2009
Antimicrobial activity and essential oil composition of a new T. argyrophyllum (C. Koch) Tvzel var. argyrophyllum chemotype.
2010
Analysis of essential oils from different organs of Scutellaria baicalensis.
2010 Aug
The chemical composition and antimicrobial activity of the leaf oil of Cupressus lusitanica from Monteverde, Costa Rica.
2010 Jan
Misidentification of tansy, Tanacetum macrophyllum, as yarrow, Achillea grandifolia: a health risk or benefit?
2010 Jan
Salvadora persica.
2010 Jul
[Analysis of the chemical constituents of volatile oil from Asarum insigne by GC-MS].
2010 Jul
A DFT analysis of thermal decomposition reactions important to natural products.
2010 Jul
The volatile constituents of Salvia leucantha.
2010 Jun
Chemical composition and antibacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum.
2010 May
Relation between developmental stage, sensory properties, and volatile content of organically and conventionally grown pac choi (Brassica rapa var. Mei Qing Choi).
2010 May
Genetics, phosphorus availability, and herbivore-derived induction as sources of phenotypic variation of leaf volatile terpenes in a pine species.
2010 Oct
Volatile oil profiles of the aerial parts of Jordanian garland, Chrysanthemum coronarium.
2010 Oct
Essential oils, phenolics, and antioxidant activities of different parts of cumin (Cuminum cyminum L.).
2010 Oct 13
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
It was shown, that bornyl acetate elevated the expression of IL-11 at both the mRNA and protein levels. Normal human chondrocytes were pretreated with or without bornyl acetate at the concentrations of 50 and 100 ug/mL for 24H, followed by incubated with IL-1b 10 ug/mL for another 24 H.
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:09:02 GMT 2025
Edited
by admin
on Mon Mar 31 19:09:02 GMT 2025
Record UNII
24QAP1VCUX
Record Status Validated (UNII)
Record Version
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Name Type Language
BORNYL ACETATE, (-)-
Systematic Name English
L-BORNYL ACETATE
FHFI  
Preferred Name English
(-)-BORNEOL ACETATE
Systematic Name English
L-BORNYL ACETATE [FHFI]
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, ACETATE, (1S-ENDO)-
Common Name English
BORNYL ACETATE, L-
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, 2-ACETATE, (1S,2R,4S)-
Common Name English
1S-ENDO-BORNYL ACETATE
Common Name English
BICYCLO(2.2.1)HEPTAN-2-OL, 1,7,7-TRIMETHYL-, ACETATE, (1S,2R,4S)-
Systematic Name English
BORNYL ACETATE L-FORM [MI]
Common Name English
BORNEOL, L-, ACETATE
Common Name English
FEMA NO. 4080
Code English
BORNYL ACETATE L-FORM
MI  
Common Name English
BORNEOL ACETATE, (-)-
Systematic Name English
(-)BRONYL ACETATE
Common Name English
(-)-BORNYL ACETATE (CONSTITUENT OF MYRRH) [DSC]
Common Name English
BORNEOL, ACETATE, (1S,2R,4S)-(-)-
Systematic Name English
LEVO-BORNYL ACETATE
Common Name English
(1S)-1,7,7-TRIMETHYLBICYCLO(2.2.1)-2-HEPTANOL ACETATE
Common Name English
(-)-BORNYL ACETATE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID3052228
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
RXCUI
2395802
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
DAILYMED
24QAP1VCUX
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
MERCK INDEX
m2611
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY Merck Index
SMS_ID
300000035078
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
FDA UNII
24QAP1VCUX
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
JECFA MONOGRAPH
1842
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
PUBCHEM
93009
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
227-101-4
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
CAS
5655-61-8
Created by admin on Mon Mar 31 19:09:02 GMT 2025 , Edited by admin on Mon Mar 31 19:09:02 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
PARENT -> CONSTITUENT ALWAYS PRESENT