CLOTHIXAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H28ClN3OS
Molecular Weight	442.017
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CLOTHIXAMIDE

Structure Search

SMILES

CNC(=O)CCN1CCN(CCC=C2C3=CC(Cl)=CC=C3SC4=C2C=CC=C4)CC1

InChI

InChIKey=WXFFTUKVTRHPLQ-UHFFFAOYSA-N

InChI=1S/C24H28ClN3OS/c1-26-24(29)10-12-28-15-13-27(14-16-28)11-4-6-19-20-5-2-3-7-22(20)30-23-9-8-18(25)17-21(19)23/h2-3,5-9,17H,4,10-16H2,1H3,(H,26,29)

HIDE SMILES / InChI

Description
Sources: https://www.sciencedirect.com/science/article/abs/pii/0024320579900961 | https://patents.google.com/patent/US3196150A/en

Clothixamide is a dopamine antagonist. The compound was invented by Pfizer in the 1960s and is claimed to be useful for the chemotherapy of mental diseases and especially for the control of excited states. Also, clothixamide is claimed to have potent antiemetic properties.

Approval Year

Name

Type

Language

CLOTHIXAMIDE

Common Name

English

1-PIPERAZINEPROPANAMIDE, 4-(3-(2-CHLORO-9H-THIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-

Systematic Name

English

4-(3-(2-CHLOROTHIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-1-PIPERAZINEPROPIONAMIDE

Systematic Name

English

clotixamide [INN]

Common Name

English

CLOTIXAMIDE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66883

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

NCI_THESAURUS

C29710

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

Code System Code Type Description

EPA CompTox

DTXSID40194593

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

CAS

4177-58-6

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

SMS_ID

100000084054

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

ChEMBL

CHEMBL2110894

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

NCI_THESAURUS

C81092

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

INN

1853

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

EVMPD

SUB06776MIG

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

FDA UNII

24623E6DZD

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

PUBCHEM

20495

Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023

PRIMARY

ACTIVE MOIETY


					24623E6DZD

SALT/SOLVATE (PARENT)


					DNS84NJF1Q

CLOTHIXAMIDE MALEATE