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Details

Stereochemistry ACHIRAL
Molecular Formula C24H28ClN3OS
Molecular Weight 442.017
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CLOTHIXAMIDE

SMILES

CNC(=O)CCN1CCN(CCC=C2C3=CC(Cl)=CC=C3SC4=C2C=CC=C4)CC1

InChI

InChIKey=WXFFTUKVTRHPLQ-UHFFFAOYSA-N
InChI=1S/C24H28ClN3OS/c1-26-24(29)10-12-28-15-13-27(14-16-28)11-4-6-19-20-5-2-3-7-22(20)30-23-9-8-18(25)17-21(19)23/h2-3,5-9,17H,4,10-16H2,1H3,(H,26,29)

HIDE SMILES / InChI
Clothixamide is a dopamine antagonist. The compound was invented by Pfizer in the 1960s and is claimed to be useful for the chemotherapy of mental diseases and especially for the control of excited states. Also, clothixamide is claimed to have potent antiemetic properties.

Approval Year

Name Type Language
CLOTHIXAMIDE
Common Name English
1-PIPERAZINEPROPANAMIDE, 4-(3-(2-CHLORO-9H-THIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-
Systematic Name English
4-(3-(2-CHLOROTHIOXANTHEN-9-YLIDENE)PROPYL)-N-METHYL-1-PIPERAZINEPROPIONAMIDE
Systematic Name English
clotixamide [INN]
Common Name English
CLOTIXAMIDE
INN  
INN  
Official Name English
Classification Tree Code System Code
NCI_THESAURUS C66883
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
NCI_THESAURUS C29710
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
Code System Code Type Description
EPA CompTox
DTXSID40194593
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
PRIMARY
CAS
4177-58-6
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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SMS_ID
100000084054
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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ChEMBL
CHEMBL2110894
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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NCI_THESAURUS
C81092
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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INN
1853
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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EVMPD
SUB06776MIG
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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FDA UNII
24623E6DZD
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
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PUBCHEM
20495
Created by admin on Sat Dec 16 16:52:29 GMT 2023 , Edited by admin on Sat Dec 16 16:52:29 GMT 2023
PRIMARY