Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H9NO6 |
| Molecular Weight | 191.1388 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12OC[C@H](O[N+]([O-])=O)[C@@]1([H])OC[C@H]2O
InChI
InChIKey=YWXYYJSYQOXTPL-JGWLITMVSA-N
InChI=1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5-,6-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Treatment of esophageal varices]. | 2001 Mar 12 |
|
| "A La Carte" treatment of portal hypertension: Adapting medical therapy to hemodynamic response for the prevention of bleeding. | 2002 Dec |
|
| Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium. | 2002 Jul |
|
| Nadolol is superior to isosorbide mononitrate for the prevention of the first variceal bleeding in cirrhotic patients with ascites. | 2002 Sep |
|
| Comparison of isosorbide mononitrate (Mono Mack) and misoprostol (Cytotec) for cervical ripening in the first trimester missed abortion. | 2005 Dec |
|
| Chronic nitrate therapy in patients with angina with comorbidity. | 2006 May-Jun |
|
| Effect of large volume injection of hydrophobic solvents on the retention of less hydrophobic pharmaceutical solutes in RP-LC. | 2008 Sep |
|
| Management of a case of endobronchial blood clot in the post operative period. | 2009 Apr |
|
| Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report. | 2009 Jan 6 |
|
| Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1. | 2010 Apr |
|
| Differences between nitrates: role of isosorbide 2-mononitrate. | 2010 Jul |
|
| Angiographic documentation of coronary artery spasm induced by anesthesia. | 2010 Jun |
|
| Rhabdomyolysis in a patient receiving ranolazine and simvastatin. | 2010 Nov 1 |
|
| Meta-analysis: isosorbide-mononitrate alone or with either beta-blockers or endoscopic therapy for the management of oesophageal varices. | 2010 Oct |
Sample Use Guides
Isosorbide 5-mononitrate (IS-5-MN) and isosorbide 2-mononitrate (IS-2-MN) kinetics were studied in two groups of young healthy subjects after intravenous injection of 5 mg of both and after oral doses of 20 mg of IS-2-MN and 10, 15, and 20 mg of IS-5-MN.
Route of Administration:
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SUB35553
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100000128484
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1353113
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16106-20-0
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62989
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240-271-4
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21BMF8FI0K
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DTXSID40873331
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admin on Sat Dec 16 07:59:07 GMT 2023 , Edited by admin on Sat Dec 16 07:59:07 GMT 2023
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PARENT (METABOLITE)
SUBSTANCE RECORD
