Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H16O6.C17H18Br2N4O2 |
| Molecular Weight | 858.528 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=N)C1=CC(Br)=C(OCCCOC2=C(Br)C=C(C=C2)C(N)=N)C=C1.OC(=O)C3=CC4=CC=CC=C4C(CC5=C(O)C(=CC6=CC=CC=C56)C(O)=O)=C3O
InChI
InChIKey=HFEFFNLWQCXXFD-UHFFFAOYSA-N
InChI=1S/C23H16O6.C17H18Br2N4O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;18-12-8-10(16(20)21)2-4-14(12)24-6-1-7-25-15-5-3-11(17(22)23)9-13(15)19/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2-5,8-9H,1,6-7H2,(H3,20,21)(H3,22,23)
DescriptionCurator's Comment: Description was created based on several sources, including http://www.goldeneyecare.co.uk/assets/Uploads/D52491-TP-GEOPL-UK-14v4-GoldenEye-Ointment-0.15.pdf | https://www.medicines.org.uk/emc/PIL.16474.latest.pdf
Curator's Comment: Description was created based on several sources, including http://www.goldeneyecare.co.uk/assets/Uploads/D52491-TP-GEOPL-UK-14v4-GoldenEye-Ointment-0.15.pdf | https://www.medicines.org.uk/emc/PIL.16474.latest.pdf
Dibrompropamidine isetionate is an antiseptic.
Ointment containing dibrompropamidine isetionate is used to treat minor eye or eyelid infections, such as conjunctivitis and blepharitis.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Studies on the mode of action of dibromopropamidine. | 1973 Jun-Aug |
|
| In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga. | 2001 |
|
| Good visual outcome after prompt treatment of acanthamoeba keratitis associated with overnight orthokeratology lens wear. | 2007 Nov |
|
| Acanthamoeba keratitis: 2007: a train wreck in slow motion. | 2007 Sep |
|
| [When the treatment is the problem]. | 2009 Feb 12 |
|
| [Graze with unusual progress]. | 2009 Feb 12 |
|
| Cosmetic contact lens-related Acanthamoeba keratitis. | 2009 May |
Sample Use Guides
Eye ointment containing dibrompropamidine isethionate 0.15% w/w to the affected eye once or twice each day for at least 2 days
Route of Administration:
Topical
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93840-61-0
Created by
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DTXSID70917595
Created by
admin on Sat Dec 16 13:44:07 GMT 2023 , Edited by admin on Sat Dec 16 13:44:07 GMT 2023
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56843770
Created by
admin on Sat Dec 16 13:44:07 GMT 2023 , Edited by admin on Sat Dec 16 13:44:07 GMT 2023
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1XH50DNH45
Created by
admin on Sat Dec 16 13:44:07 GMT 2023 , Edited by admin on Sat Dec 16 13:44:07 GMT 2023
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SUBSTANCE RECORD
