COLTEROL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H19NO3
Molecular Weight	225.2842
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of COLTEROL

Structure Search

SMILES

CC(C)(C)NCC(O)C1=CC=C(O)C(O)=C1

InChI

InChIKey=PHSMOUBHYUFTDM-UHFFFAOYSA-N

InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-5-9(14)10(15)6-8/h4-6,11,13-16H,7H2,1-3H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7820101 | https://www.ncbi.nlm.nih.gov/pubmed/3895171 | https://www.drugbank.ca/drugs/DB00901

Colterol is a beta-2 adrenoreceptor agonist. Bitolterol, a diester prodrug of colterol, was marketed by Elan Pharmaceuticals for the treatment of reversible bronchospasm associated with asthma or chronic obstructive pulmonary diseases.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Beta-2 adrenergic receptor 203 Target ID: CHEMBL210 Sources: https://www.ncbi.nlm.nih.gov/pubmed/2993621	Agonist 2678		600.0 nM [Kd]

Name

Type

Language

COLTEROL

Official Name

English

KWD-2026

Code

English

1,2-BENZENEDIOL, 4-(2-)((1,1-DIMETHYLETHYL)AMINO)-1-HYDROXYETHYL)- (±)-

Common Name

English

1,2-BENZENEDIOL, 4-(2-((1,1-DIMETHYLETHYL)AMINO)-1-HYDROXYETHYL)-

Systematic Name

English

colterol [INN]

Common Name

English

S-1541

Code

English

(±)-.ALPHA.-((TERT-BUTYLAMINO)METHYL)-3,4-DIHYDROXYBENZYL ALCOHOL

Systematic Name

English

WIN-5563

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C48149

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

Code System Code Type Description

CHEBI

73085

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

ChEMBL

CHEMBL1159715

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

PUBCHEM

25104

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

NCI_THESAURUS

C76018

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

MESH

C011595

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

INN

4058

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

EVMPD

SUB06802MIG

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

FDA UNII

1WH11068UO

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

EPA CompTox

DTXSID40864860

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

SMS_ID

100000084266

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

CAS

18866-78-9

Created by admin on Fri Dec 15 15:59:49 GMT 2023 , Edited by admin on Fri Dec 15 15:59:49 GMT 2023

PRIMARY

ACTIVE MOIETY


					1WH11068UO

COLTEROL

PRODRUG (METABOLITE ACTIVE)


					9KY0QXD6LI

SALT/SOLVATE (PARENT)


					25CJR2TJPW

COLTEROL MESYLATE