FENALCOMINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C20H27NO2
Molecular Weight	313.4339
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FENALCOMINE

Structure Search

SMILES

CCC(O)C1=CC=C(OCCNC(C)CC2=CC=CC=C2)C=C1

InChI

InChIKey=DOBLSWXRNYSVDC-UHFFFAOYSA-N

InChI=1S/C20H27NO2/c1-3-20(22)18-9-11-19(12-10-18)23-14-13-21-16(2)15-17-7-5-4-6-8-17/h4-12,16,20-22H,3,13-15H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://link.springer.com/chapter/10.1007/978-1-4757-2085-3_6 | https://www.ncbi.nlm.nih.gov/pubmed/1134178 | https://www.ncbi.nlm.nih.gov/pubmed/779586 | http://www.druglead.com/cds/Fenalcomine.html

Fenalcomine is a coronary vasodilator, cardiotonic and local anesthetic agent. It was studied in the treatment of angina pectoris.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Fenalcomine hydrochloride inhibits the action of PG on the smooth muscle but stimulates that of TXA2.	1980	7386277
[Clinical study of fenalcomine chlorhydrate in 30 cases of angina pectoris].	1976-05-01	779586
[Study of the action of fenalcomine chlorhydrate using ergometric tests].	1975-05-01	1096749
[Clinical study of a new anti-angina pectoris agent: Fenalcomine hydrochloride].	1975-01	1134178

Patents

Patents

Name

Type

Language

FENALCOMINE

Official Name

English

FENALCOMINE [MI]

Preferred Name

English

.ALPHA.-ETHYL-P-(2-((.ALPHA.-METHYLPHENETHYL)AMINO)ETHOXY)BENZYL ALCOHOL

Common Name

English

fenalcomine [INN]

Common Name

English

Fenalcomine [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707

Created by admin on Wed Apr 02 09:13:37 GMT 2025 , Edited by admin on Wed Apr 02 09:13:37 GMT 2025

Code System Code Type Description

CAS

34616-39-2

Created by admin on Wed Apr 02 09:13:37 GMT 2025 , Edited by admin on Wed Apr 02 09:13:37 GMT 2025

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SMS_ID

100000081241

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ChEMBL

CHEMBL2106300

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EPA CompTox

DTXSID10865723

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INN

3380

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DRUG CENTRAL

1144

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MERCK INDEX

m184

Created by admin on Wed Apr 02 09:13:37 GMT 2025 , Edited by admin on Wed Apr 02 09:13:37 GMT 2025

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Merck Index

NCI_THESAURUS

C65636

Created by admin on Wed Apr 02 09:13:37 GMT 2025 , Edited by admin on Wed Apr 02 09:13:37 GMT 2025

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MESH

C001424

Created by admin on Wed Apr 02 09:13:37 GMT 2025 , Edited by admin on Wed Apr 02 09:13:37 GMT 2025

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FDA UNII

1TBQ3A47P8

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PUBCHEM

71934

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EVMPD

SUB07536MIG

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ACTIVE MOIETY


					1TBQ3A47P8