ARACHIDYL ALCOHOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H42O
Molecular Weight	298.5469
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCCCO

InChI

InChIKey=BTFJIXJJCSYFAL-UHFFFAOYSA-N

InChI=1S/C20H42O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h21H,2-20H2,1H3

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Antiatherosclerotic function of Kokuto, Okinawan noncentrifugal cane sugar.	2009-01-14	19072226
Gas chromatographic determination of high molecular weight alcohols from policosanol in omega-3 fish oil by acylation with acetyl chloride.	2008-11-05	18980113
COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma.	2008-11	18753249
Lack of effect of sugar cane and sunflower seed policosanols on plasma cholesterol in rabbits.	2008-08	18978167
Octacosanol isolated from Tinospora cordifolia downregulates VEGF gene expression by inhibiting nuclear translocation of NF-B and its DNA binding activity.	2008-07-07	18513715
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo.	2008-07	18495798
Identification of chemical compounds from the leaves of Leea indica.	2008-06	18515230
Changes in cholesterol kinetics following sugar cane policosanol supplementation: a randomized control trial.	2008-04-30	18447941
Effects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative study.	2008-04-05	18388038
Sugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled study.	2008-04	18514906
Effects of emulsified policosanols with different chain lengths on cholesterol metabolism in heterozygous LDL receptor-deficient mice.	2008-04	18162663
Novel molecular precursor of lanthanide complexes with long chain mono cis-butene dicarboxylate to the controlled synthesis of Y2O3:Eu3+ phosphors.	2008-03	18468122
Octacosanol attenuates disrupted hepatic reactive oxygen species metabolism associated with acute liver injury progression in rats intoxicated with carbon tetrachloride.	2008-03	18385828
Effect of sugar cane policosanol on lipid profile in primary hypercholesterolemia.	2008-03	18167048
Does the solid-liquid crystal phase transition provoke the spin-state change in spin-crossover metallomesogens?	2008-01-30	18181626
Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth.	2008	18670614
Effects of D-003, a mixture of very long chain saturated fatty acids, and policosanol on in vivo lipid peroxidation in rats.	2008	18488809
Rice policosanol does not have any effects on blood coagulation factors in hypercholesterolemic patients.	2007-12	18217459
The odor of origin: kinship and geographical distance are reflected in the marking pheromone of male beewolves (Philanthus triangulum F., Hymenoptera, Crabronidae).	2007-10-10	17927833
Protective effect of policosanol on endothelium and intimal thickness induced by forceps in rabbits.	2007-09	17887938
Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters.	2007-09	17123537
Comparison of various extraction methods for policosanol from rice bran wax and establishment of chromatographic fingerprint of policosanol.	2007-07-11	17564456
Photophysical properties of novel ternary lanthanide complexes with long chain mono-L cis-butene dicarboxylate (L = hexadecyl, octadecyl and eicosyl) and 2,2'-bipyridyl (or 1,10-phenanthroline).	2007-05	17440798
Competency-based evaluation tools for integrative medicine training in family medicine residency: a pilot study.	2007-04-18	17442108
Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial.	2007-03-26	17386092
Dietary supplements for the prevention and treatment of coronary artery disease.	2007-02-21	17309382
Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigation.	2007	17341006
PolicosanolPlus and Neuroprevin ameliorate pesticide-mediated inhibition of neurite outgrowth and neurite degeneration.	2006-12	17136002
Comparative lipid-lowering effects of policosanol and atorvastatin: a randomized, parallel, double-blind, placebo-controlled trial.	2006-11	17070175
Complementary and alternative therapies for the management of dyslipidemia.	2006-11	17047144
Policosanol: a sweet nothing for high cholesterol.	2006-09	17131532
Policosanol inhibits cholesterol synthesis in hepatoma cells by activation of AMP-kinase.	2006-09	16714400
Policosanol content and composition in perilla seeds.	2006-07-26	16848517
Interfacial rheology and structure of straight-chain and branched fatty alcohol mixtures.	2006-06-06	16732659
Toward a core nutraceutical program for cancer management.	2006-06	16685077
New policosanol product combines natural cholesterol lowering with omega-3 fatty acids to lower CV risk.	2006-05-31	16733605
Effect of policosanol on lipid levels among patients with hypercholesterolemia or combined hyperlipidemia: a randomized controlled trial.	2006-05-17	16705107
Effects of a policosanol supplement on serum lipid concentrations in hypercholesterolaemic and heterozygous familial hypercholesterolaemic subjects.	2006-05	16611388
[A randomized, double-blind, placebo-controlled study of the antilipemic efficacy and tolerability of food supplement policosanol in patients with moderate hypercholesterolemia].	2006-04-06	16583932
[Chemical constituents analysis of policosanol by GC and GC/MS].	2006-03	16830483
Effects of policosanol on patients with ischemic stroke: a pilot open study.	2006	17004902
Toward prevention of Alzheimers disease--potential nutraceutical strategies for suppressing the production of amyloid beta peptides.	2006	16828233
Adjuvant strategies for prevention of glomerulosclerosis.	2006	16828231
Down-regulation of microglial activation may represent a practical strategy for combating neurodegenerative disorders.	2006	16513287
Spectroscopic study on the photophysical properties of novel lanthanide complexes with long chain mono-L phthalate (L=hexadecyl, octadecyl and eicosyl).	2005-11	16257724
Policosanol has no antioxidant activity in human low-density lipoprotein but increases excretion of bile acids in hamsters.	2005-08-10	16076108
Effects of rice policosanol on serum lipoproteins, homocysteine, fibrinogen and C-reactive protein in hypercholesterolaemic patients.	2005	17532716
A comparison of the effects of D-003 and policosanol (5 and 10 mg/day) in patients with type II hypercholesterolemia: a randomized, double-blinded study.	2005	16444910
Protective effect of policosanol on atherosclerotic plaque on aortas in monkeys.	2004-07-14	16099319
Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation in patients with dyslipidaemia and type 2 diabetes mellitus.	2003	17535079

Patents

Name

Type

Language

1-EICOSANOL

Preferred Name

English

ARACHIDYL ALCOHOL

Official Name

English

EICOSYL ALCOHOL

Systematic Name

English

ARACHIDIC ALCOHOL

Common Name

English

ARACHIDYL ALCOHOL [USP-RS]

Common Name

English

ARACHIC ALCOHOL

Common Name

English

1-EICOSANOL [HSDB]

Common Name

English

1-ICOSANOL

Systematic Name

English

NSC-120887

Code

English

Code System Code Type Description

PUBCHEM

12404