ARACHIDYL ALCOHOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H42O
Molecular Weight	298.5469
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCCCCCCO

InChI

InChIKey=BTFJIXJJCSYFAL-UHFFFAOYSA-N

InChI=1S/C20H42O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21/h21H,2-20H2,1H3

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Effects of policosanol 20 versus 40 mg/day in the treatment of patients with type II hypercholesterolemia: a 6-month double-blind study.	2001	11708574
A long-term study of policosanol in the treatment of intermittent claudication.	2001 Feb	11228084
Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk.	2001 Mar	11253161
Comparison of the efficacy, safety and tolerability of original policosanol versus other mixtures of higher aliphatic primary alcohols in patients with type II hypercholesterolemia.	2002	12503776
Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent.	2002 Feb	11835043
Inhibition of rat lipoprotein lipid peroxidation by the oral administration of D003, a mixture of very long-chain saturated fatty acids.	2002 Jan	11911221
Physico-mechanical characterization of policosanol, a novel hypocholesterolemic drug.	2002 Jan	11858528
Study of the interaction between policosanol and excipients.	2002 Mar-Apr	12135162
Study of the stability of tablets containing 10 mg of policosanol as active principle.	2002 May-Jun	12197422
Validation of a gas chromatographic method for determination of fatty alcohols in 10 mg film-coated tablets of policosanol.	2002 May-Jun	12083248
Comparison of the efficacy and tolerability of policosanol with atorvastatin in elderly patients with type II hypercholesterolaemia.	2003	12534315
Effects of policosanols and phytosterols on lipid levels and cholesterol biosynthesis in hamsters.	2003 Feb	12733749
Stability studies of tablets containing 5 mg of policosanol.	2003 Sep	14677271
IGF-I activity may be a key determinant of stroke risk--a cautionary lesson for vegans.	2003 Sep	12944100
Wheat germ policosanol failed to lower plasma cholesterol in subjects with normal to mildly elevated cholesterol concentrations.	2004 Oct	15375787
Effects of concurrent therapy with policosanol and omega-3 fatty acids on lipid profile and platelet aggregation in rabbits.	2005	15806713
An ezetimibe-policosanol combination has the potential to be an OTC agent that could dramatically lower LDL cholesterol without side effects.	2005	15617880
Complementary care. How statin alternatives stack up. Some help control cholesterol; others are potentially harmful.	2005 Jan	15795954
In vitro and in vivo study of octacosanol metabolism.	2005 Mar-Apr	15847942
[A randomized, double-blind, placebo-controlled study of the antilipemic efficacy and tolerability of food supplement policosanol in patients with moderate hypercholesterolemia].	2005 Nov-Dec	16583932
Down-regulation of microglial activation may represent a practical strategy for combating neurodegenerative disorders.	2006	16513287
Effects of a policosanol supplement on serum lipid concentrations in hypercholesterolaemic and heterozygous familial hypercholesterolaemic subjects.	2006 May	16611388
Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigation.	2007	17341006
Rice policosanol does not have any effects on blood coagulation factors in hypercholesterolemic patients.	2007 Dec	18217459
Protective effect of policosanol on endothelium and intimal thickness induced by forceps in rabbits.	2007 Sep	17887938
Lack of effect of sugar cane policosanol on plasma cholesterol in Golden Syrian hamsters.	2007 Sep	17123537
Effects of emulsified policosanols with different chain lengths on cholesterol metabolism in heterozygous LDL receptor-deficient mice.	2008 Apr	18162663
Octacosanol attenuates disrupted hepatic reactive oxygen species metabolism associated with acute liver injury progression in rats intoxicated with carbon tetrachloride.	2008 Mar	18385828

Patents

Name

Type

Language

ARACHIDYL ALCOHOL

Official Name

English

EICOSYL ALCOHOL

Systematic Name

English

ARACHIDIC ALCOHOL

Common Name

English

ARACHIDYL ALCOHOL [INCI]

Common Name

English

ARACHIDYL ALCOHOL [USP-RS]

Common Name

English

ARACHIC ALCOHOL

Common Name

English

1-EICOSANOL [HSDB]

Common Name

English

1-ICOSANOL

Systematic Name

English

1-EICOSANOL

Systematic Name

English

NSC-120887

Code

English

Code System Code Type Description

PUBCHEM

12404